Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy

Quansheng Cheng; Qingcheng Wang; Songnan Qu

doi:10.1038/s41377-025-01757-6

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Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy

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- Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy
- Light: Science & Applications Vol. 14, Issue 4, Pages: 880-883(2025)
- Affiliations：
  
  1.Joint Key Laboratory of the Ministry of Education, Institute of Applied Physics and Materials Engineering, University of Macau, Taipa, Macau SAR 999078, China
  2.Department of Physics and Chemistry, Faculty of Science and Technology, University of Macau, Taipa, Macau SAR 999078, China
- Author bio：
  
  Songnan Qu (songnanqu@um.edu.mo)
- Funds：
- DOI：10.1038/s41377-025-01757-6
  CLC：
- Published Online：27 February 2025，
  
  Published：30 April 2025
- Accepted：
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Cheng, Q. S., Wang, Q. C. & Qu, S. N. Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy. Light: Science & Applications, 14, 880-883 (2025).
DOI：

Cheng, Q. S., Wang, Q. C. & Qu, S. N. Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy. Light: Science & Applications, 14, 880-883 (2025). DOI： 10.1038/s41377-025-01757-6.

摘要

Abstract

A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting

pH response

near-infrared fluorescence imaging

and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.

关键词

Keywords

references

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