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Volume 14  Issue 11,2025 2025年第14卷第11 Issue
  • News & Views

    Xi Xie, Yijie Shen

    DOI:10.1038/s41377-025-01969-w
    Abstract:Optical vortices carrying angular momenta have promising applications from ultra-capacity communication to ultraprecise metrology, especially boosted by their recent on-chip developments. Now, the 6th-generation optical vortex technology has been unraveled by an all-on-chip integrated platform, with fully reconfigurable vector vortex control of arbitrary spin-to-orbital angular momentum coupling.  
      
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    Xinman Yin, Yanyu Zhao

    DOI:10.1038/s41377-025-01944-5
    Abstract:An open, dynamic, and electromagnetically invisible space has been constructed using reconfigurable metasurfaces and self-play reinforcement learning. A model named MetaSeeker is proposed to optimize the cloaking performance of randomly distributed metasurfaces. The hidden objects can move freely within the constructed invisible space, with environmental similarity of 99.5%. This advancement provides an innovative solution for cloaking technologies in complex environments.  
      
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    Luciano A. Masullo

    DOI:10.1038/s41377-025-01980-1
    Abstract:A new high-precision single-molecule localization scheme, ISM-FLUX, is an implementation of MINFLUX using image-scanning microscopy (ISM) with a single-photon avalanche diode (SPAD) array detector. ISM-FLUX results in a larger localization range, enhancing the robustness of the localization scheme and it also potentially enables experiments in which absorption and emission of a single fluorophore can be probed independently.  
      
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    Jinbing Hu, Yixin Sha, Yi Yang

    DOI:10.1038/s41377-025-02038-y
    Abstract:A photonic synthetic angular-momentum lattice realizes non-Hermitian topological edge modes that are jointly determined by the eigenstate and eigenenergy winding numbers.  
      
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    Dingxin Huang, Yung Doug Suh, Guanying Chen

    DOI:10.1038/s41377-025-02033-3
    Abstract:Tuning the emissive chromaticity of parallel photon avalanches in Ho3+-doped nanoparticles with dual reservoir levels enables multicolor super-resolution imaging under 965 nm single wavelength continuous-wave excitation.  
      
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    Zi-Jun Guo, Geng-Bo Wu

    DOI:10.1038/s41377-025-02037-z
    Abstract:By combining substrate-side, phase-cancelling reflection with monolayer graphene reconfigured as nanoscale tunable lateral capacitors within metasurface unit cells, terahertz amplitude modulation exceeding 40 dB at around 2 THz with 30 MHz reconfiguration speed is demonstrated under solid-state, room-temperature conditions. The design provides a scalable and practical platform for high-speed, large-dynamic-range terahertz communications, real-time imaging, and programmable photonic circuits.  
      
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  • Editorial

    Xi-Cheng Zhang, Yun-Feng Xiao

    DOI:10.1038/s41377-025-01938-3
      
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    Updated:2025-11-21
  • Light People

    Chenzi Guo, Peng Wang

    DOI:10.1038/s41377-025-02012-8
    Abstract:Professor Wei Lu is a leading scientist in infrared physics. He proposed the paradigm of localized manipulation over electrons and photons for infrared detection, addressing the critical challenge of dark current suppression in long-wave infrared detectors. His direct observation of the Haldane gap in quasi-one-dimensional magnetic materials was one of the earliest experimental validations of the Haldane’s conjecture - a crucial step in the theoretical discoveries of topological phases of matter that led to 2016 Nobel Prize in Physics for Duncan Haldane. Beyond fundamental research, Prof. Lu and his team developed a series of new advanced infrared detectors on multiple remote sensing satellite platforms. During his tenure as the Director of China’s State Key Laboratory of Infrared Physics and President of the Shanghai Institute of Technical Physics (SITP) at the Chinese Academy of Sciences, he led the strategic development of the institutions, contributing to China’s breakthroughs in spaceborne remote sensing technologies.  
      
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  • Research Highlight

    Eric Mazur

    DOI:10.1038/s41377-025-01964-1
      
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  • Reviews

    Chenxi Wang, Qiang Yu, Ming Li, Haoyi Chen, Huizhen Fan, Yingying Ma, Zhitao Zhang, Mei X. Wu, Min Lu

    DOI:10.1038/s41377-025-01990-z
    Abstract:Phototherapy offers advantages of non-invasiveness, cost-effectiveness, localized treatment, and potential for home-based care across various medical conditions. However, its adoption is hindered by the large size, limited safety, and professional operation requirements of current phototherapeutic devices. Unlike bulky laser phototherapeutic devices, wearable and implantable LED-based devices overcome these limitations, offering improved safety, portability, and uniform light distribution, making them promising prototypes for next-generation phototherapies. This review explores the home-care potentials of phototherapy from a clinical application perspective and provides a comprehensive overview of its therapeutic mechanisms and diverse applications. By synthesizing the latest advancements and cutting-edge research, we identify key clinical challenges associated with wearable and implantable phototherapy devices and propose fundamental strategies to address these limitations, such as miniaturization, biocompatibility, and energy efficiency. Furthermore, we draw on interdisciplinary cutting-edge research to address the challenges faced by phototherapy devices. We also emphasize the critical value of integrating artificial intelligence (AI) and flexible sensing technologies within phototherapy systems. Specific methods and potential applications are discussed for effectively integrating phototherapy systems with AI algorithms to establish a closed-loop diagnostic and therapeutic system. Grounded in clinical applications, we outline concrete research directions for developing next-generation LED-based phototherapy devices. This review delivers valuable insights for clinicians leveraging phototherapy and offers a roadmap for researchers in material science, flexible electronics, and AI, fostering interdisciplinary innovations to advance future phototherapy applications.  
      
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