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Volume 15 Issue 3，2026
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Abstract：Bound states in the continuum (BICs) provide a route to strong, long-range photonic coupling with dynamic tunability. Recent advances demonstrate that BIC metasurfaces enable reconfigurable two-dimensional coupling between arbitrarily positioned resonators, with the added capability of ultrafast all-optical control.3|0|0Updated：2026-04-14- Abstract：A novel NIR light-activated CRISPR-dCas9/Cas9 system achieves precise and rapid gene regulation in living organism using a chemically cleavable rapamycin dimer. Unlike previous light-driven systems, this approach offers deeper tissue penetration, low toxicity, fast response, and minimal background activity. This platform opens new directions for highly efficient, targeted, noninvasive, and spatially confined gene editing for a great number of preclinical and clinically translatable applications.3|0|0Updated：2026-04-14
- Abstract：The ability to create complex three-dimensional structures of light is extremely challenging. Now, a technique combining Dammann optimization with metasurfaces has been developed, enabling control over all parameters, including polarization, phase, angular momentum, and spatial modes. The generation of three-dimensional generalized vortex beams can open new horizons for their applications in photonics.3|0|0Updated：2026-04-14
- Abstract：A high-performance miniaturized on-chip spectral imager operating in the ultraviolet region is demonstrated based on an AlGaN/GaN cascaded photodiode array. This work extends spectral imaging into the ultraviolet regimes by leveraging the mature Ⅲ-nitride technologies and establishes a scalable pathway toward massive production of compact, high-resolution spectral imagers.3|0|0Updated：2026-04-14
Original Articles
Abstract：High-throughput trapping and precision manipulation of individual pathogenic bioparticles in complex microenvironments are of great importance for in-vitro diagnostics and drug screening. Although optical tweezers have been widely used for bioparticle trapping and manipulation, the throughput, functionality, and adaptability are still limited for on-chip integrated bioparticle manipulation in complex and dynamic bioenvironments. Here, we report flexible, stretchable, on-chip optical tweezers (FSOT) based on large-scale orderly assembled microlenses for high-throughput manipulation of bioparticles in complex bio-environments and on flexible substrates, including soft bio-substrates such as skin and intestines. Large-scale (up to 1000) photonic nanojet effect of the microlenses enables high-throughput trapping, sorting, and modulation of individual bioparticles with sizes ranging from sub-100 nm to tens of micrometers, such as exosomes, bacteria and mammalian cells. Our FSOT exhibits high flexibility, which enables bioparticle trapping and sorting in complex and curved biological microenvironments. Importantly, our FSOT also exhibits high deformability and stretchability, which facilitates the control of inter-cellular distance between trapped neighboring cells, enabling real-time modulating and monitoring the interaction between single pathogenic bacteria and macrophage. Our FSOT represents a new class of on-chip optical tweezers for high-throughput bioparticle trapping and manipulation with the features of high flexibility and stretchability, and holds great promises as an integrated on-chip platform for high-throughput dynamic analysis of bioparticles, for revealing inter-cellular interactions between pathogenic bioparticles and host cells, and for precise drug screening.3|0|0Updated：2026-04-14- Abstract：Trapped ions are a promising modality for quantum systems, with demonstrated utility as the basis for quantum processors and optical clocks. However, traditional trapped-ion systems are implemented using complex free-space optical configurations, whose large size and susceptibility to vibrations and drift inhibit scaling to large numbers of qubits. In recent years, integrated-photonics-based systems have been demonstrated as an avenue to address the challenge of scaling trapped-ion systems while maintaining high fidelities. While these previous demonstrations have implemented both Doppler and resolved-sideband cooling of trapped ions, these cooling techniques are fundamentally limited in efficiency. In contrast, polarization-gradient cooling can enable faster and more power-efficient cooling and, therefore, improved computational efficiencies in trapped-ion systems. While free-space implementations of polarization-gradient cooling have demonstrated advantages over other cooling mechanisms, polarization-gradient cooling has never previously been implemented using integrated photonics. In this paper, we design and experimentally demonstrate key polarization-diverse integrated-photonics devices and utilize them to implement a variety of integrated-photonics-based polarization-gradient-cooling systems, culminating in the first experimental demonstration of polarization-gradient cooling of a trapped ion by an integrated-photonics-based system. By demonstrating polarization-gradient cooling using an integrated-photonics-based system and, in general, opening up the field of polarization-diverse integrated-photonics-based devices and systems for trapped ions, this work facilitates new capabilities for integrated-photonics-based trapped-ion platforms.3|0|0Updated：2026-04-14
- Abstract：Accurate transverse displacement measurement is essential for precise mask-to-wafer positioning in lithography. While lateral displacement metrology has achieved nanometer-level precision, the limitations imposed by coherent state and grating challenge in-situ measurement speed and precision. Here, we introduce a two-photon state transverse displacement measurement method utilizing a polarization gradient metasurface by employing two-photon state interference. Compared with the classical method, our new method can experimentally reduce the number of detected photons to around 3% with equivalent precision. These attributes make the two-photon state polarization gradient metasurface approach highly suitable for integration with semiconductor lithography processes and show its promise in realizing equivalent measurement precision within notably shorter acquisition durations, providing a robust solution for next-generation transverse displacement measurement requirements.3|0|0Updated：2026-04-14
- Abstract：Coherent light detection and ranging (LiDAR) has become an indispensable tool in autonomous systems, offering exceptional precision and ambient-light immunity. Recently, applications spanning from scientific research to advanced manufacturing have increasingly required resolution that exceeds current capabilities, which faces a fundamental trade-off between improved performance and system complexity. In this study, we overcome the intrinsic limitation and present a cavity dynamics-enabled approach that actively enhances the ranging resolution through phase multiplication. By injecting target-scattered light into the optical resonator, the operating frequency of the laser undergoes periodic modulation, generating interference harmonics that multiply the phase sensitivity. Experimentally, we observe the excitation of up to the 13th-order harmonic and effective phase multiplication without physical modulation extensions, which enables more than 10 times resolution enhancement for ranging. Owing to the intrinsic phase correlation between the fundamental wave and harmonic waves, the phase noise is effectively controlled, resulting in high-precision ranging with a standard deviation on the order of tens of micrometers. The system concurrently leverages laser feedback sensitivity, achieving significant signal-to-noise ratio (SNR) improvement. With its enhanced resolution, low photon consumption, and low-cost implementation, this technology demonstrates new capabilities that promise to enable a wide range of applications.3|0|0Updated：2026-04-14
- Abstract：Mid-infrared semiconductor lasers operating in the 2.0–5.0 μm spectral range play an important role for various applications, including trace-gas detection, biomedical analysis, and free-space optical communication. InP-based quantum-well (QW) and quantum-dash (Qdash) lasers are promising alternatives to conventional GaSb-based QW lasers because of their lower cost and mature fabrication infrastructure. However, they suffer from high threshold current density (Jth) and limited operation temperatures. InAs/InP quantum-dot (QD) lasers theoretically offer lower Jth owing to their three-dimensional carrier confinement. Nevertheless, achieving high-density, uniform InAs/InP QDs with sufficient gain for lasing over 2 μm remains a major challenge. Here, we report the first demonstration of mid-infrared InAs/InP QD lasers emitting beyond 2 μm. Five-stack InAs/In0.532Ga0.468As/InP QDs grown by molecular-beam epitaxy exhibit room-temperature photoluminescence at 2.04 μm. Edge-emitting lasers achieve lasing at 2.018 μm with a low Jth of 589 A cm−2 and a maximum operation temperature of 50 ℃. Notably, the Jth per layer (118 A cm−2) is the lowest ever reported for room-temperature InP-based mid-infrared lasers, outperforming QW/Qdash counterparts. These results pave the way for a new class of low-cost, high-performance mid-infrared light sources using InAs/InP QDs, marking a notable step forward in the development of mid-infrared semiconductor lasers.3|0|0Updated：2026-04-14
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