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    Vol. 13 Issue 10 2024

      News & Views

    • Cheng Wang
      Vol. 13, Issue 10, Pages: 1985-1986(2024) DOI: 10.1038/s41377-024-01551-w
      Abstract:A universal design strategy for dispersive elements in anisotropic platforms is proposed, enabling high-performance arrayed waveguide gratings in thin-film lithium niobate that are essential for future optical communications.  
        
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    • Hyeonsu Heo,Junsuk Rho
      Vol. 13, Issue 10, Pages: 1987-1989(2024) DOI: 10.1038/s41377-024-01552-9
      Abstract:Limited information capacity and inter-channel crosstalk in metaholograms hinder their practical use in display applications. Leveraging waveguide-based metasurfaces, the integration of spin and angle-of-incidence multiplexing facilitates the generation of broadband six-channel metaholograms free from crosstalk.  
        
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    • Yichen Cai,Xiangyu Hou,Wei Chen
      Vol. 13, Issue 10, Pages: 1990-1991(2024) DOI: 10.1038/s41377-024-01553-8
      Abstract:The discrete preparation of functional layers followed by lamination for all-organic active-matrix organic light-emitting diodes enables an ultrahigh aperture ratio and reliable conformability, promising significant potential for next-generation skin-like displays.  
        
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    • Haiyan Ou
      Vol. 13, Issue 10, Pages: 1992-1994(2024) DOI: 10.1038/s41377-024-01515-0
      Abstract:Silicon carbide (SiC) is emerging as a promising material platform for quantum photonic integrated circuits (QPICs). A quantum light source is one of the fundamental building blocks for QPICs. A high-performance quantum light source from SiC platform will facilitate SiC's infiltration into QPICs.  
        
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    • Isaac Nape,Andrew Forbes
      Vol. 13, Issue 10, Pages: 1995-1996(2024) DOI: 10.1038/s41377-024-01575-2
      Abstract:Transparent objects are invisible to traditional cameras because they can only detect intensity fluctuations, necessitating the need for interferometry followed by computationally intensive digital image processing. Now it is shown that the necessary transformations can be performed optically by combining machine learning and diffractive optics, for a direct in-situ measurement of transparent objects with conventional cameras.  
        
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    • Dawn T. H. Tan,Xavier X. Chia
      Vol. 13, Issue 10, Pages: 1997-1999(2024) DOI: 10.1038/s41377-024-01576-1
      Abstract:Ultra-low loss silicon nitride realized using deuterated precursors and low thermal budgets well within backend-of-line CMOS processing may accelerate widespread proliferation of their use.  
        
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    • Hou-Tong Chen
      Vol. 13, Issue 10, Pages: 2000-2001(2024) DOI: 10.1038/s41377-024-01579-y
      Abstract:Structured light beams offer promising properties for a variety of applications, but the generation of broadband structured light remains a challenge. New opportunities are emerging in the terahertz frequency range owing to recent progress in light-driven ultrafast vectorial currents through spatially patterning spintronic and optoelectronic systems.  
        
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      Published:2024-10-15

      Light People

    • Tingting Sun
      Vol. 13, Issue 10, Pages: 2002-2007(2024) DOI: 10.1038/s41377-024-01583-2
      Abstract:Professor Juejun Hu was admitted by Tsinghua University as top scorer in the science college entrance examination of Fujian Province. After graduating, he went to MIT to pursue further studies, where he continued to excel and became a faculty member. Each step of his journey has been marked by extraordinary achievements, setting a standard that few can match. Today, Prof. Hu is recognized as a leading expert in integrated photonics and optical materials. His pioneering research has not only advanced the frontiers of academia but also made significant impacts on industrial applications. In this interview, we invite you to delve into Prof. Hu's research world, exploring his unique insights into technological innovation and how he uses the power of science to shape the future.  
        
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      Research Highlight

    • Hang Chen,Fei Dai
      Vol. 13, Issue 10, Pages: 2008(2024) DOI: 10.1038/s41377-024-01571-6
        
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      Reviews

    • Yuan Luo,Jiaxin Zhao,Antonio Fieramosca,Quanbing Guo,Haifeng Kang,Xiaoze Liu,Timothy C. H. Liew,Daniele Sanvitto,Zhiyuan An,Sanjib Ghosh,Ziyu Wang,Hongxing Xu,Qihua Xiong
      Vol. 13, Issue 10, Pages: 2009-2026(2024) DOI: 10.1038/s41377-024-01523-0
      Abstract:In recent years, two-dimensional (2D) van der Waals materials have emerged as a focal point in materials research, drawing increasing attention due to their potential for isolating and synergistically combining diverse atomic layers. Atomically thin transition metal dichalcogenides (TMDs) are one of the most alluring van der Waals materials owing to their exceptional electronic and optical properties. The tightly bound excitons with giant oscillator strength render TMDs an ideal platform to investigate strong light-matter coupling when they are integrated with optical cavities, providing a wide range of possibilities for exploring novel polaritonic physics and devices. In this review, we focused on recent advances in TMD-based strong light-matter coupling. In the foremost position, we discuss the various optical structures strongly coupled to TMD materials, such as Fabry-Perot cavities, photonic crystals, and plasmonic nanocavities. We then present several intriguing properties and relevant device applications of TMD polaritons. In the end, we delineate promising future directions for the study of strong light-matter coupling in van der Waals materials.  
        
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    • Chuang Yang,Wenjing Hu,Jiale Liu,Chuanzhou Han,Qiaojiao Gao,Anyi Mei,Yinhua Zhou,Fengwan Guo,Hongwei Han
      Vol. 13, Issue 10, Pages: 2027-2074(2024) DOI: 10.1038/s41377-024-01461-x
      Abstract:In just over a decade, certified single-junction perovskite solar cells (PSCs) boast an impressive power conversion efficiency (PCE) of 26.1%. Such outstanding performance makes it highly viable for further development. Here, we have meticulously outlined challenges that arose during the industrialization of PSCs and proposed their corresponding solutions based on extensive research. We discussed the main challenges in this field including technological limitations, multi-scenario applications, sustainable development, etc. Mature photovoltaic solutions provide the perovskite community with invaluable insights for overcoming the challenges of industrialization. In the upcoming stages of PSCs advancement, it has become evident that addressing the challenges concerning long-term stability and sustainability is paramount. In this manner, we can facilitate a more effective integration of PSCs into our daily lives.  
        
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    • Guanzhong Pan,Meng Xun,Xiaoli Zhou,Yun Sun,Yibo Dong,Dexin Wu
      Vol. 13, Issue 10, Pages: 2075-2100(2024) DOI: 10.1038/s41377-024-01561-8
      Abstract:Vertical cavity surface emitting lasers (VCSELs) have emerged as a versatile and promising platform for developing advanced integrated photonic devices and systems due to their low power consumption, high modulation bandwidth, small footprint, excellent scalability, and compatibility with monolithic integration. By combining these unique capabilities of VCSELs with the functionalities offered by micro/nano optical structures (e.g. metasurfaces), it enables various versatile energy-efficient integrated photonic devices and systems with compact size, enhanced performance, and improved reliability and functionality. This review provides a comprehensive overview of the state-of-the-art versatile integrated photonic devices/systems based on VCSELs, including photonic neural networks, vortex beam emitters, holographic devices, beam deflectors, atomic sensors, and biosensors. By leveraging the capabilities of VCSELs, these integrated photonic devices/systems open up new opportunities in various fields, including artificial intelligence, large-capacity optical communication, imaging, biosensing, and so on. Through this comprehensive review, we aim to provide a detailed understanding of the pivotal role played by VCSELs in integrated photonics and highlight their significance in advancing the field towards efficient, compact, and versatile photonic solutions.  
        
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    • Michael John Fanous,Paloma Casteleiro Costa,Çağatay Işıl,Luzhe Huang,Aydogan Ozcan
      Vol. 13, Issue 10, Pages: 2101-2113(2024) DOI: 10.1038/s41377-024-01544-9
      Abstract:In recent years, the integration of deep learning techniques with biophotonic setups has opened new horizons in bioimaging. A compelling trend in this field involves deliberately compromising certain measurement metrics to engineer better bioimaging tools in terms of e.g., cost, speed, and form-factor, followed by compensating for the resulting defects through the utilization of deep learning models trained on a large amount of ideal, superior or alternative data. This strategic approach has found increasing popularity due to its potential to enhance various aspects of biophotonic imaging. One of the primary motivations for employing this strategy is the pursuit of higher temporal resolution or increased imaging speed, critical for capturing fine dynamic biological processes. Additionally, this approach offers the prospect of simplifying hardware requirements and complexities, thereby making advanced imaging standards more accessible in terms of cost and/or size. This article provides an in-depth review of the diverse measurement aspects that researchers intentionally impair in their biophotonic setups, including the point spread function (PSF), signal-to-noise ratio (SNR), sampling density, and pixel resolution. By deliberately compromising these metrics, researchers aim to not only recuperate them through the application of deep learning networks, but also bolster in return other crucial parameters, such as the field of view (FOV), depth of field (DOF), and space-bandwidth product (SBP). Throughout this article, we discuss various biophotonic methods that have successfully employed this strategic approach. These techniques span a wide range of applications and showcase the versatility and effectiveness of deep learning in the context of compromised biophotonic data. Finally, by offering our perspectives on the exciting future possibilities of this rapidly evolving concept, we hope to motivate our readers from various disciplines to explore novel ways of balancing hardware compromises with compensation via artificial intelligence (AI).  
        
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      Original Articles

    • Jingzhong Yang,Zenghui Jiang,Frederik Benthin,Joscha Hanel,Tom Fandrich,Raphael Joos,Stephanie Bauer,Sascha Kolatschek,Ali Hreibi,Eddy Patrick Rugeramigabo,Michael Jetter,Simone Luca Portalupi,Michael Zopf,Peter Michler,Stefan Kück,Fei Ding
      Vol. 13, Issue 10, Pages: 2114-2123(2024) DOI: 10.1038/s41377-024-01488-0
      Abstract:Quantum key distribution (QKD) enables the transmission of information that is secure against general attacks by eavesdroppers. The use of on-demand quantum light sources in QKD protocols is expected to help improve security and maximum tolerable loss. Semiconductor quantum dots (QDs) are a promising building block for quantum communication applications because of the deterministic emission of single photons with high brightness and low multiphoton contribution. Here we report on the first intercity QKD experiment using a bright deterministic single photon source. A BB84 protocol based on polarisation encoding is realised using the high-rate single photons in the telecommunication C-band emitted from a semiconductor QD embedded in a circular Bragg grating structure. Utilising the 79 km long link with 25.49 dB loss (equivalent to 130 km for the direct-connected optical fibre) between the German cities of Hannover and Braunschweig, a record-high secret key bits per pulse of 4.8 × 10−5 with an average quantum bit error ratio of ~ 0.65% are demonstrated. An asymptotic maximum tolerable loss of 28.11 dB is found, corresponding to a length of 144 km of standard telecommunication fibre. Deterministic semiconductor sources therefore challenge state-of-the-art QKD protocols and have the potential to excel in measurement device independent protocols and quantum repeater applications.  
        
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    • Rusong Li,Yunfei Xu,Shichen Zhang,Yu Ma,Junhong Liu,Binru Zhou,Lijun Wang,Ning Zhuo,Junqi Liu,Jinchuan Zhang,Shenqiang Zhai,Shuman Liu,Fengqi Liu,Quanyong Lu
      Vol. 13, Issue 10, Pages: 2124-2130(2024) DOI: 10.1038/s41377-024-01567-2
      Abstract:High-power terahertz (THz) quantum cascade laser, as an emerging THz solid-state radiation source, is attracting attention for numerous applications including medicine, sensing, and communication. However, due to the sub-wavelength confinement of the waveguide structure, direct beam brightness upscaling with device area remains elusive due to several mode competition and external optical lens is normally used to enhance the THz beam brightness. Here, we propose a metallic THz photonic crystal resonator with a phase-engineered design for single mode surface emission over a broad area. The quantum cascade surface-emitting laser is capable of delivering an output peak power over 185 mW with a narrow beam divergence of 4.4° × 4.4° at 3.88 THz. A high beam brightness of 1.6 × 107 W sr−1m−2 with near-diffraction-limited M2 factors of 1.4 in both vertical and lateral directions is achieved from a large device area of 1.6 × 1.6 mm2 without using any optical lenses. The adjustable phase shift between the lattices enables a stable and high-intensity surface emission over a broad device area, which makes it an ideal light extractor for large-scale THz emitters. Our research paves the way to high brightness solid-state THz lasers and facilitates new applications in standoff THz imaging, detection, and diagnosis.  
        
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    • Haishan Liu,Fei Wang,Ying Jin,Xianzheng Ma,Siteng Li,Yaoming Bian,Guohai Situ
      Vol. 13, Issue 10, Pages: 2131-2144(2024) DOI: 10.1038/s41377-024-01569-0
      Abstract:Imaging through dynamic scattering media is one of the most challenging yet fascinating problems in optics, with applications spanning from biological detection to remote sensing. In this study, we propose a comprehensive learning-based technique that facilitates real-time, non-invasive, incoherent imaging of real-world objects through dense and dynamic scattering media. We conduct extensive experiments, demonstrating the capability of our technique to see through turbid water and natural fog. The experimental results indicate that the proposed technique surpasses existing approaches in numerous aspects and holds significant potential for imaging applications across a broad spectrum of disciplines.  
        
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    • Shuang Hao,Sartanee Suebka,Judith Su
      Vol. 13, Issue 10, Pages: 2145-2155(2024) DOI: 10.1038/s41377-024-01536-9
      Abstract:Label-free detection techniques for single particles and molecules play an important role in basic science, disease diagnostics, and nanomaterial investigations. While fluorescence-based methods are tools for single molecule detection and imaging, they are limited by available molecular probes and photoblinking and photobleaching. Photothermal microscopy has emerged as a label-free imaging technique capable of detecting individual nanoabsorbers with high sensitivity. Whispering gallery mode (WGM) microresonators can confine light in a small volume for enhanced light-matter interaction and thus are a promising ultra-sensitive photothermal microscopy platform. Previously, microtoroid optical resonators were combined with photothermal microscopy to detect 250 nm long gold nanorods and 100 nm long polymers. Here, we combine microtoroids with photothermal microscopy to spatially detect single 5 nm diameter quantum dots (QDs) with a signal-to-noise ratio exceeding 104. Photothermal images were generated by point-by-point scanning of the pump laser. Single particle detection was confirmed for 18 nm QDs by high sensitivity fluorescence imaging and for 5 nm QDs via comparison with theory. Our system demonstrates the capability to detect a minimum heat dissipation of 0.75 pW. To achieve this, we integrated our microtoroid based photothermal microscopy setup with a low amplitude modulated pump laser and utilized the proportional-integral-derivative controller output as the photothermal signal source to reduce noise and enhance signal stability. The heat dissipation of these QDs is below that from single dye molecules. We anticipate that our work will have application in a wide variety of fields, including the biological sciences, nanotechnology, materials science, chemistry, and medicine.  
        
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    • Yifeng Shao,Sven Weerdenburg,Jacob Seifert,H. Paul Urbach,Allard P. Mosk,Wim Coene
      Vol. 13, Issue 10, Pages: 2156-2167(2024) DOI: 10.1038/s41377-024-01558-3
      Abstract:Ptychographic extreme ultraviolet (EUV) diffractive imaging has emerged as a promising candidate for the next generationmetrology solutions in the semiconductor industry, as it can image wafer samples in reflection geometry at the nanoscale. This technique has surged attention recently, owing to the significant progress in high-harmonic generation (HHG) EUV sources and advancements in both hardware and software for computation. In this study, a novel algorithm is introduced and tested, which enables wavelength-multiplexed reconstruction that enhances the measurement throughput and introduces data diversity, allowing the accurate characterisation of sample structures. To tackle the inherent instabilities of the HHG source, a modal approach was adopted, which represents the cross-density function of the illumination by a series of mutually incoherent and independent spatial modes. The proposed algorithm was implemented on a mainstream machine learning platform, which leverages automatic differentiation to manage the drastic growth in model complexity and expedites the computation using GPU acceleration. By optimising over 200 million parameters, we demonstrate the algorithm's capacity to accommodate experimental uncertainties and achieve a resolution approaching the diffraction limit in reflection geometry. The reconstruction of wafer samples with 20-nm high patterned gold structures on a silicon substrate highlights our ability to handle complex physical interrelations involving a multitude of parameters. These results establish ptychography as an efficient and accurate metrology tool.  
        
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    • Guangyou Liu,Xinzao Wu,Feng Xiong,Jinglan Yang,Yunhe Liu,Jie Liu,Zhuohang Li,Zong Qin,Shaozhi Deng,Bo-Ru Yang
      Vol. 13, Issue 10, Pages: 2168-2178(2024) DOI: 10.1038/s41377-024-01526-x
      Abstract:Traditional optical anti-counterfeiting (AC) is achieved by static printed images, which makes them susceptible to lower levels of security and easier replication. Therefore, it is essential to develop AC device with dynamic modulation for higher security. Electrophoretic display (EPD) has the advantages of low power consumption, high ambient contrast ratio, and capability of showing dynamic images which is suitable for dynamic AC applications. Herein, we prepared a dynamical AC device based on a fluorescent EPD, and achieving the image switch between black, white, and green fluorescence states under the dual-mode driving (electronic field and UV light). We loaded perovskite quantum dots (CsPbBr3) onto the TiO2 particles and further prepared fluorescent electrophoretic particles TiO2/CsPbBr3-3-PLMA (TiO/CPB-3) by grafting and polymerizing method. In addition, we fabricated the AC devices based on the fluorescent EPD, which exhibits the multifunctional AC, where the fluorescent EPD has a fast response time of 350 ms, a high contrast ratio of 17, and bright green fluorescence. This prototype demonstrates a new way for future dynamic AC and identification.  
        
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    • Ana S. Sotirova,Bangshan Sun,Jamie D. Leppard,Andong Wang,Mohan Wang,Andres Vazquez-Brennan,David P. Nadlinger,Simon Moser,Alexander Jesacher,Chao He,Fabian Pokorny,Martin J. Booth,Christopher J. Ballance
      Vol. 13, Issue 10, Pages: 2179-2191(2024) DOI: 10.1038/s41377-024-01542-x
      Abstract:Individual optical addressing in chains of trapped atomic ions requires the generation of many small, closely spaced beams with low cross-talk. Furthermore, implementing parallel operations necessitates phase, frequency, and amplitude control of each individual beam. Here, we present a scalable method for achieving all of these capabilities using a high-performance integrated photonic chip coupled to a network of optical fibre components. The chip design results in very low cross-talk between neighbouring channels even at the micrometre-scale spacing by implementing a very high refractive index contrast between the channel core and cladding. Furthermore, the photonic chip manufacturing procedure is highly flexible, allowing for the creation of devices with an arbitrary number of channels as well as non-uniform channel spacing at the chip output. We present the system used to integrate the chip within our ion trap apparatus and characterise the performance of the full individual addressing setup using a single trapped ion as a light-field sensor. Our measurements showed intensity cross-talk below ~10–3 across the chip, with minimum observed cross-talk as low as ~10–5.  
        
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    • Federico Vismarra,Marina Fernández-Galán,Daniele Mocci,Lorenzo Colaizzi,Víctor Wilfried Segundo,Roberto Boyero-García,Javier Serrano,Enrique Conejero-Jarque,Marta Pini,Lorenzo Mai,Yingxuan Wu,Hans Jakob Wörner,Elisa Appi,Cord L. Arnold,Maurizio Reduzzi,Matteo Lucchini,Julio San Román,Mauro Nisoli,Carlos Hernández-García,Rocío Borrego-Varillas
      Vol. 13, Issue 10, Pages: 2192-2200(2024) DOI: 10.1038/s41377-024-01564-5
      Abstract:Isolated attosecond pulse (IAP) generation usually involves the use of short-medium gas cells operated at high pressures. In contrast, long-medium schemes at low pressures are commonly perceived as inherently unsuitable for IAP generation due to the nonlinear phenomena that challenge favourable phase-matching conditions. Here we provide clear experimental evidence on the generation of isolated extreme-ultraviolet attosecond pulses in a semi-infinite gas cell, demonstrating the use of extended-medium geometries for effective production of IAPs. To gain a deeper understanding we develop a simulation method for high-order harmonic generation (HHG), which combines nonlinear propagation with macroscopic HHG solving the 3D time-dependent Schrödinger equation at the single-atom level. Our simulations reveal that the nonlinear spatio-temporal reshaping of the driving field, observed in the experiment as a bright plasma channel, acts as a self-regulating mechanism boosting the phase-matching conditions for the generation of IAPs.  
        
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    • Huaxu Liang,Xinping Zhang,Fuqiang Wang,Chunzhe Li,Weizhe Yuan,Weifeng Meng,Ziming Cheng,Yan Dong,Xuhang Shi,Yuying Yan,Hongliang Yi,Yong Shuai,Yi Long
      Vol. 13, Issue 10, Pages: 2201-2211(2024) DOI: 10.1038/s41377-024-01525-y
      Abstract:Thermochromic hydrogels exhibit a smart capacity for regulating solar spectrum transmission, enabling automatically change their transmissivity in response to the ambient temperature change. This has great importance for energy conservation purposes. Military and civilian emergency thermochromic applications require rapid visible-light stealth (VLS); however, concurrent smart solar transmission and rapid VLS is yet to be realized. Inspired by squid-skin, we propose a micropatterned thermochromic hydrogel (MTH) to realize the concurrent control of smart solar transmittance and rapid VLS at all-working temperatures. The MTH possesses two optical regulation mechanisms: optical property regulation and optical scattering, controlled by temperature and pressure, respectively. The introduced surface micropattern strategy can arbitrarily switch between normal and diffuse transmission, and the VLS response time is within 1 s compared with previous ~180 s. The MTH also has a high solar-transmission regulation range of 61%. Further, the MTH preparation method is scalable and cost-effective. This novel regulation mechanism opens a new pathway towards applications with multifunctional optical requirements.  
        
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    • Yi Sun,Jordan Stone,Xiyuan Lu,Feng Zhou,Junyeob Song,Zhimin Shi,Kartik Srinivasan
      Vol. 13, Issue 10, Pages: 2212-2220(2024) DOI: 10.1038/s41377-024-01534-x
      Abstract:Optical parametric oscillation (OPO) in Kerr microresonators can efficiently transfer near-infrared laser light into the visible spectrum. To date, however, chromatic dispersion has mostly limited output wavelengths to > 560 nm, and robust access to the whole green light spectrum has not been demonstrated. In fact, wavelengths between 532 nm and 633 nm, commonly referred to as the "green gap", are especially challenging to produce with conventional laser gain. Hence, there is motivation to extend the Kerr OPO wavelength range and develop reliable device designs. Here, we experimentally show how to robustly access the entire green gap with Kerr OPO in silicon nitride microrings pumped near 780 nm. Our microring geometries are optimized for green-gap emission; in particular, we introduce a dispersion engineering technique, based on partially undercutting the microring, which not only expands wavelength access but also proves robust to variations in resonator dimensions. Using just four devices, we generate > 150 wavelengths evenly distributed throughout the green gap, as predicted by our dispersion simulations. Moreover, we establish the usefulness of Kerr OPO to coherent applications by demonstrating continuous frequency tuning (> 50 GHz) and narrow optical linewidths (< 1 MHz). Our work represents an important step in the quest to bring nonlinear nanophotonics and its advantages to the visible spectrum.  
        
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    • Qihang Zhang,Ajinkya Pandit,Zhiguang Liu,Zhen Guo,Shashank Muddu,Yi Wei,Deborah Pereg,Neda Nazemifard,Charles Papageorgiou,Yihui Yang,Wenlong Tang,Richard D. Braatz,Allan S. Myerson,George Barbastathis
      Vol. 13, Issue 10, Pages: 2221-2230(2024) DOI: 10.1038/s41377-024-01563-6
      Abstract:Non-invasive characterization of powders may take one of two approaches: imaging and counting individual particles; or relying on scattered light to estimate the particle size distribution (PSD) of the ensemble. The former approach runs into practical difficulties, as the system must conform to the working distance and other restrictions of the imaging optics. The latter approach requires an inverse map from the speckle autocorrelation to the particle sizes. The principle relies on the pupil function determining the basic sidelobe shape, whereas the particle size spread modulates the sidelobe intensity. We recently showed that it is feasible to invert the speckle autocorrelation and obtain the PSD using a neural network, trained efficiently through a physics-informed semi-generative approach. In this work, we eliminate one of the most time-consuming steps of our previous method by engineering the pupil function. By judiciously blocking portions of the pupil, we sacrifice some photons but in return we achieve much enhanced sidelobes and, hence, higher sensitivity to the change of the size distribution. The result is a 60 × reduction in total acquisition and processing time, or 0.25 seconds per frame in our implementation. Almost real-time operation in our system is not only more appealing toward rapid industrial adoption, it also paves the way for quantitative characterization of complex spatial or temporal dynamics in drying, blending, and other chemical and pharmaceutical manufacturing processes.  
        
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    • Yibo Huang,Yao Lu,Wei Li,Xitan Xu,Xinda Jiang,Ruobin Ma,Lu Chen,Ningjuan Ruan,Qiang Wu,Jingjun Xu
      Vol. 13, Issue 10, Pages: 2231-2239(2024) DOI: 10.1038/s41377-024-01509-y
      Abstract:Optical Kerr effect, in which input light intensity linearly alters the refractive index, has enabled the generation of optical solitons, supercontinuum spectra, and frequency combs, playing vital roles in the on-chip devices, fiber communications, and quantum manipulations. Especially, terahertz Kerr effect, featuring fascinating prospects in future high-rate computing, artificial intelligence, and cloud-based technologies, encounters a great challenge due to the rather low power density and feeble Kerr response. Here, we demonstrate a giant terahertz frequency Kerr nonlinearity mediated by stimulated phonon polaritons. Under the influences of the giant Kerr nonlinearity, the power-dependent refractive index change would result in a frequency shift in the microcavity, which was experimentally demonstrated via the measurement of the resonant mode of a chip-scale lithium niobate Fabry-Pérot microcavity. Attributed to the existence of stimulated phonon polaritons, the nonlinear coefficient extracted from the frequency shifts is orders of magnitude larger than that of visible and infrared light, which is also theoretically demonstrated by nonlinear Huang equations. This work opens an avenue for many rich and fruitful terahertz Kerr effect based physical, chemical, and biological systems that have terahertz fingerprints.  
        
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      Published:2024-10-15
    • Giulia Crotti,Mert Akturk,Andrea Schirato,Vincent Vinel,Anton A. Trifonov,Ivan C. Buchvarov,Dragomir N. Neshev,Remo Proietti Zaccaria,Paolo Laporta,Aristide Lemaître,Giuseppe Leo,Giulio Cerullo,Margherita Maiuri,Giuseppe Della Valle
      Vol. 13, Issue 10, Pages: 2240-2250(2024) DOI: 10.1038/s41377-024-01545-8
      Abstract:Switching of light polarization on the sub-picosecond timescale is a crucial functionality for applications in a variety of contexts, including telecommunications, biology and chemistry. The ability to control polarization at ultrafast speed would pave the way for the development of unprecedented free-space optical links and of novel techniques for probing dynamical processes in complex systems, as chiral molecules. Such high switching speeds can only be reached with an all-optical paradigm, i.e., engineering active platforms capable of controlling light polarization via ultrashort laser pulses. Here we demonstrate giant modulation of dichroism and birefringence in an all-dielectric metasurface, achieved at low fluences of the optical control beam. This performance, which leverages the many degrees of freedom offered by all-dielectric active metasurfaces, is obtained by combining a high-quality factor nonlocal resonance with the giant third-order optical nonlinearity dictated by photogenerated hot carriers at the semiconductor band edge.  
        
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      Published:2024-10-15
    • Gong Zhang,Yue Chen,Zijie Zheng,Rui Shao,Jiuren Zhou,Zuopu Zhou,Leming Jiao,Jishen Zhang,Haibo Wang,Qiwen Kong,Chen Sun,Kai Ni,Jixuan Wu,Jiezhi Chen,Xiao Gong
      Vol. 13, Issue 10, Pages: 2251-2262(2024) DOI: 10.1038/s41377-024-01555-6
      Abstract:To reduce system complexity and bridge the interface between electronic and photonic circuits, there is a high demand for a non-volatile memory that can be accessed both electrically and optically. However, practical solutions are still lacking when considering the potential for large-scale complementary metal-oxide semiconductor compatible integration. Here, we present an experimental demonstration of a non-volatile photonic-electronic memory based on a 3-dimensional monolithic integrated ferroelectric-silicon ring resonator. We successfully demonstrate programming and erasing the memory using both electrical and optical methods, assisted by optical-to-electrical-to-optical conversion. The memory cell exhibits a high optical extinction ratio of 6.6 dB at a low working voltage of 5 V and an endurance of 4 × 104 cycles. Furthermore, the multi-level storage capability is analyzed in detail, revealing stable performance with a raw bit-error-rate smaller than 5.9 × 10−2. This ground-breaking work could be a key technology enabler for future hybrid electronic-photonic systems, targeting a wide range of applications such as photonic interconnect, high-speed data communication, and neuromorphic computing.  
        
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      Published:2024-10-15
    • Igor Meglinski,Ivan Lopushenko,Anton Sdobnov,Alexander Bykov
      Vol. 13, Issue 10, Pages: 2263-2275(2024) DOI: 10.1038/s41377-024-01562-7
      Abstract:Recent advancements in wavefront shaping techniques have facilitated the study of complex structured light's propagation with orbital angular momentum (OAM) within various media. The introduction of spiral phase modulation to the Laguerre–Gaussian (LG) beam during its paraxial propagation is facilitated by the negative gradient of the medium's refractive index change over time, leading to a notable increase in the rate of phase twist, effectively observed as phase retardation of the OAM. This approach attains remarkable sensitivity to even the slightest variations in the medium's refractive index (~10−6). The phase memory of OAM is revealed as the ability of twisted light to preserve the initial helical phase even propagating through the turbid tissue-like multiple scattering medium. The results confirm fascinating opportunities for exploiting OAM light in biomedical applications, e.g. such as non-invasive trans-cutaneous glucose diagnosis and optical communication through biological tissues and other optically dense media.  
        
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      Published:2024-10-15
    • Chuangchuang Chen,Honggang Gu,Shiyuan Liu
      Vol. 13, Issue 10, Pages: 2276-2287(2024) DOI: 10.1038/s41377-024-01581-4
      Abstract:Strict requirement of a coherent spectrum in coherent diffractive imaging (CDI) architectures poses a significant obstacle to achieving efficient photon utilization across the full spectrum. To date, nearly all broadband computational imaging experiments have relied on accurate spectroscopic measurements, as broad spectra are incompatible with conventional CDI systems. This paper presents an advanced approach to broaden the scope of CDI to ultra-broadband illumination with unknown probe spectrum, effectively addresses the key challenges encountered by existing state-of-the-art broadband diffractive imaging frameworks. This advancement eliminates the necessity for prior knowledge of probe spectrum and relaxes constraints on non-dispersive samples, resulting in a significant extension in spectral bandwidth, achieving a nearly fourfold improvement in bandlimit compared to the existing benchmark. Our method not only monochromatizes a broadband diffraction pattern from unknown illumination spectrum, but also determines the compressive sampled profile of spectrum of the diffracted radiation. This superiority is experimentally validated using both CDI and ptychography techniques on an ultra-broadband supercontinuum with relative bandwidth exceeding 40%, revealing a significantly enhanced coherence and improved reconstruction with high fidelity under ultra-broadband illumination.  
        
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      Published:2024-10-15
    • Wei Li,Junjie Lin,Wanyi Huang,Qingrou Wang,Haoran Zhang,Xuejie Zhang,Jianle Zhuang,Yingliang Liu,Songnan Qu,Bingfu Lei
      Vol. 13, Issue 10, Pages: 2288-2299(2024) DOI: 10.1038/s41377-024-01518-x
      Abstract:In the era of smart agriculture, the precise labeling and recording of growth information in plants pose challenges for modern agricultural production. This study introduces strontium aluminate particles coated with H3PO4 as luminescent labels capable of spatial embedding within plants for information encoding and storage during growth. The encapsulation with H3PO4 imparts stability and enhanced luminescence to SrAl2O4: Eu2+, Dy3+ (SAO). Using SAO@H3PO4 as a low-damage luminescent label, we implement its delivery into plants through microneedles (MNs) patches. The embedded SAO@H3PO4 within plants exhibits sustained and unaltered high signal-to-noise afterglow emission, with luminous intensity remaining at approximately 78% of the original for 27 days. To cater to diverse information recording needs, MNs of various geometric shapes are designed for loading SAO@H3PO4, and the luminescent signals in different shapes can be accurately identified through a designed program, the corresponding information can be conveniently viewed on a computer. Additionally, inspired by binary information concepts, MNs patches with specific arrangements of luminescent and non-luminescent points are created, resulting in varied luminescent MNs arrays on leaves. An advanced camera system with a tailored program accurately identifies and maps the labels to the corresponding recorded information. These findings showcase the potential of low-damage luminescent labels within plants, paving the way for convenient and widespread storage of plant growth information.  
        
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      Published:2024-10-15
    • Jose Ilton De Oliveira Filho,Abderrahmen Trichili,Omar Alkhazragi,Mohamed-Slim Alouini,Boon S. Ooi,Khaled Nabil Salama
      Vol. 13, Issue 10, Pages: 2300-2311(2024) DOI: 10.1038/s41377-024-01566-3
      Abstract:Simultaneous lightwave information and power transfer (SLIPT), co-existing with optical wireless communication, holds an enormous potential to provide continuous charging to remote Internet of Things (IoT) devices while ensuring connectivity. Combining SLIPT with an omnidirectional receiver, we can leverage a higher power budget while maintaining a stable connection, a major challenge for optical wireless communication systems. Here, we design a multiplexed SLIPT-based system comprising an array of photodetectors (PDs) arranged in a 3 × 3 configuration. The system enables decoding information from multiple light beams while simultaneously harvesting energy. The PDs can swiftly switch between photoconductive and photovoltaic modes to maximize information transfer rates and provide on-demand energy harvesting. Additionally, we investigated the ability to decode information and harvest energy with a particular quadrant set of PDs from the array, allowing beam tracking and spatial diversity. The design was explored in a smaller version for higher data rates and a bigger one for higher power harvesting. We report a self-powering device that can achieve a gross data rate of 25.7 Mbps from a single-input single-output (SISO) and an 85.2 Mbps net data rate in a multiple-input multiple-output (MIMO) configuration. Under a standard AMT1.5 illumination, the device can harvest up to 87.33 mW, around twice the power needed to maintain the entire system. Our work paves the way for deploying autonomous IoT devices in harsh environments and their potential use in space applications.  
        
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      Published:2024-10-15
    • Yogeshwar Nath Mishra,Peng Wang,Florian J. Bauer,Murthy S. Gudipati,Lihong V. Wang
      Vol. 13, Issue 10, Pages: 2312-2320(2024) DOI: 10.1038/s41377-024-01588-x
      Abstract:The creation of carbonaceous nanoparticles and their dynamics in hydrocarbon flames are still debated in environmental, combustion, and material sciences. In this study, we introduce single-pulse femtosecond laser sheet-compressed ultrafast photography (fsLS-CUP), an ultrafast imaging technique specifically designed to shed light on and capture ultrafast dynamics stemming from interactions between femtosecond lasers and nanoparticles in flames in a single-shot. fsLS-CUP enables the first-time real-time billion frames-per-second (Gfps) simultaneous two-dimensional (2D) imaging of laser-induced fluorescence (LIF) and laser-induced heating (LIH) that are originated from polycyclic aromatic hydrocarbons (PAHs) and soot particles, respectively. Furthermore, fsLS-CUP provides the real-time spatiotemporal map of femtosecond laser-soot interaction as elastic light scattering (ELS) at an astonishing 250 Gfps. In contrast to existing single-shot ultrafast imaging approaches, which are limited to millions of frames per second only and require multiple laser pulses, our method employs only a single pulse and captures the entire dynamics of laser-induced signals at hundreds of Gfps. Using a single pulse does not change the optical properties of nanoparticles for a following pulse, thus allowing reliable spatiotemporal mapping. Moreover, we found that particle inception and growth are derived from precursors. In essence, as an imaging modality, fsLS-CUP offers ultrafast 2D diagnostics, contributing to the fundamental understanding of nanoparticle's inception and broader applications across different fields, such as material science and biomedical engineering.  
        
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      Published:2024-10-15
    • Kai Han,Jiance Jin,Yuzhen Wang,Xinquan Zhou,Yongsheng Sun,Lihan Chen,Zhiguo Xia
      Vol. 13, Issue 10, Pages: 2321-2330(2024) DOI: 10.1038/s41377-024-01589-w
      Abstract:Luminescent metal halides are attracting growing attention as scintillators for X-ray imaging in safety inspection, medical diagnosis, etc. Here we present brand-new hybrid Eu(Ⅱ)-bromide scintillators, 1D type [Et4N]EuBr3·MeOH and 0D type [Me4N]6Eu5Br16·MeOH, with spin-allowed 5d-4f bandgap transition emission toward simplified carrier transport during scintillation process. The 1D/0D structures with edge/face -sharing [EuBr6]4− octahedra further contribute to lowing bandgaps and enhancing quantum confinement effect, enabling efficient scintillation performance (light yield ~73100 ± 800 Ph MeV−1, detect limit ~18.6 nGy s−1, X-ray afterglow ~ 1% @ 9.6 μs). We demonstrate the X-ray imaging with 27.3 lp mm−1 resolution by embedding Eu(Ⅱ)-based scintillators into AAO film. Our results create the new family of low-dimensional rare-earth-based halides for scintillation and related optoelectronic applications.  
        
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      Published:2024-10-15
    • Ruicong Zhang,Zicheng Song,Wenxin Cao,Gang Gao,Lei Yang,Yurong He,Jiecai Han,Zhibo Zhang,Tianyu Wang,Jiaqi Zhu
      Vol. 13, Issue 10, Pages: 2331-2341(2024) DOI: 10.1038/s41377-024-01541-y
      Abstract:A novel multispectral smart window has been proposed, which features dynamic modulation of light transmittance and effective shielding against electromagnetic microwave radiation. This design integrates liquid crystal dynamic scattering and dye doping techniques, enabling the dual regulation of transmittance and scattering within a single-layer smart window. Additionally, the precise control of conductive film thickness ensures the attainment of robust microwave signal shielding. We present a theoretical model for ion movement in the presence of an alternating electric field, along with a novel approach to manipulate negative dielectric constant. The proposed model successfully enables a rapid transition between light transparent, absorbing and haze states, with an optimum drive frequency adjustable to approximately 300 Hz. Furthermore, the resistive design of the conductive layer effectively mitigates microwave radiation within the 2−18 GHz range. These findings offer an innovative perspective for future advancements in environmental construction.  
        
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      Published:2024-10-15
    • Yunxiang Song,Yaowen Hu,Xinrui Zhu,Kiyoul Yang,Marko Lončar
      Vol. 13, Issue 10, Pages: 2342-2352(2024) DOI: 10.1038/s41377-024-01546-7
      Abstract:Dissipative Kerr solitons from optical microresonators, commonly referred to as soliton microcombs, have been developed for a broad range of applications, including precision measurement, optical frequency synthesis, and ultra-stable microwave and millimeter wave generation, all on a chip. An important goal for microcombs is self-referencing, which requires octave-spanning bandwidths to detect and stabilize the comb carrier envelope offset frequency. Further, detection and locking of the comb spacings are often achieved using frequency division by electro-optic modulation. The thin-film lithium niobate photonic platform, with its low loss, strong second- and third-order nonlinearities, as well as large Pockels effect, is ideally suited for these tasks. However, octave-spanning soliton microcombs are challenging to demonstrate on this platform, largely complicated by strong Raman effects hindering reliable fabrication of soliton devices. Here, we demonstrate entirely connected and octave-spanning soliton microcombs on thin-film lithium niobate. With appropriate control over microresonator free spectral range and dissipation spectrum, we show that soliton-inhibiting Raman effects are suppressed, and soliton devices are fabricated with near-unity yield. Our work offers an unambiguous method for soliton generation on strongly Raman-active materials. Further, it anticipates monolithically integrated, self-referenced frequency standards in conjunction with established technologies, such as periodically poled waveguides and electro-optic modulators, on thin-film lithium niobate.  
        
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      Published:2024-10-15
    • Chiho Yoon,Eunwoo Park,Sampa Misra,Jin Young Kim,Jin Woo Baik,Kwang Gi Kim,Chan Kwon Jung,Chulhong Kim
      Vol. 13, Issue 10, Pages: 2353-2366(2024) DOI: 10.1038/s41377-024-01554-7
      Abstract:In pathological diagnostics, histological images highlight the oncological features of excised specimens, but they require laborious and costly staining procedures. Despite recent innovations in label-free microscopy that simplify complex staining procedures, technical limitations and inadequate histological visualization are still problems in clinical settings. Here, we demonstrate an interconnected deep learning (DL)-based framework for performing automated virtual staining, segmentation, and classification in label-free photoacoustic histology (PAH) of human specimens. The framework comprises three components: (1) an explainable contrastive unpaired translation (E-CUT) method for virtual H&E (VHE) staining, (2) an U-net architecture for feature segmentation, and (3) a DL-based stepwise feature fusion method (StepFF) for classification. The framework demonstrates promising performance at each step of its application to human liver cancers. In virtual staining, the E-CUT preserves the morphological aspects of the cell nucleus and cytoplasm, making VHE images highly similar to real H&E ones. In segmentation, various features (e.g., the cell area, number of cells, and the distance between cell nuclei) have been successfully segmented in VHE images. Finally, by using deep feature vectors from PAH, VHE, and segmented images, StepFF has achieved a 98.00% classification accuracy, compared to the 94.80% accuracy of conventional PAH classification. In particular, StepFF's classification reached a sensitivity of 100% based on the evaluation of three pathologists, demonstrating its applicability in real clinical settings. This series of DL methods for label-free PAH has great potential as a practical clinical strategy for digital pathology.  
        
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      Published:2024-10-15
    • Gyunghun Kim,Joseph Suh,Dayeong Lee,Namkyoo Park,Sunkyu Yu
      Vol. 13, Issue 10, Pages: 2367-2375(2024) DOI: 10.1038/s41377-024-01557-4
      Abstract:The presence of long-range interactions is crucial in distinguishing between abstract complex networks and wave systems. In photonics, because electromagnetic interactions between optical elements generally decay rapidly with spatial distance, most wave phenomena are modeled with neighboring interactions, which account for only a small part of conceptually possible networks. Here, we explore the impact of substantial long-range interactions in topological photonics. We demonstrate that a crystalline structure, characterized by long-range interactions in the absence of neighboring ones, can be interpreted as an overlapped lattice. This overlap model facilitates the realization of higher values of topological invariants while maintaining bandgap width in photonic topological insulators. This breaking of topology-bandgap tradeoff enables topologically protected multichannel signal processing with broad bandwidths. Under practically accessible system parameters, the result paves the way to the extension of topological physics to network science.  
        
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      Published:2024-10-15
    • Muhammad Afnan Ansari,Hammad Ahmed,Yan Li,Guanchao Wang,Jemma E. Callaghan,Ruoxing Wang,James Downing,Xianzhong Chen
      Vol. 13, Issue 10, Pages: 2376-2388(2024) DOI: 10.1038/s41377-024-01565-4
      Abstract:Metalenses can integrate the functionalities of multiple optical components thanks to the unprecedented capability of optical metasurfaces in light control. With the rapid development of optical metasurfaces, metalenses continue to evolve. Polarization and color play a very important role in understanding optics and serve as valuable tools for gaining insights into our world. Benefiting from the design flexibility of metasurfaces, we propose and experimentally demonstrate a super metalens that can realize multifaceted control of focal points along any 3D curved trajectory. The wavelengths and polarization states of all focal points are engineered in a desirable manner. The super metalens can simultaneously realize customized 3D positioning, polarization states, and wavelengths of focal points, which are experimentally demonstrated with incident wavelengths ranging from 501 to 700 nm. We further showcase the application of the developed super metalenses in 3D optical distance measurement. The compact nature of metasurfaces and unique properties of the proposed super metalenses hold promise to dramatically miniaturize and simplify the optical architecture for applications in optical metrology, imaging, detection, and security.  
        
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      Published:2024-10-15
    • Yongkang Zhang,Jie Zheng,Fangzhou Jin,Jie Xiao,Ni Lan,Zhiyuan Xu,Xu Yue,Zesen Li,Chengzhi Li,Donglin Cao,Yifei Wang,Wenbin Zhong,Yang Ran,Bai-Ou Guan
      Vol. 13, Issue 10, Pages: 2389-2404(2024) DOI: 10.1038/s41377-024-01586-z
      Abstract:Chemotherapy is one of the conventional treatments for cancer in clinical practice. However, poor delivery efficiency, systemic toxicity, and the lack of pharmacokinetic monitoring during treatment are the critical limitations of current chemotherapy. Herein, we reported a brand-new antitumor drug delivery strategy that harnesses an optical fiber endoscopically therapeutic probe. The fiber probe carries photosensitizers in the fiber core and antitumor agents on the fiber surface mediated by a temperature-responsive hydrogel film, giving rise to an activable photothermal-chemotherapy that orchestrates the localized hyperthermia and thermal-stimuli drug release to the tumor lesion. Furthermore, the dynamical drug release and in-situ temperature can be real-time supervised through the built-in fiber sensors, including the reflective Mach–Zehnder interferometer and fiber Bragg grating, to visualize the therapy process and thus improve the safety of treatment. Compared with conventional methods, the fiber-optic drug delivery can adequately take advantage of the chemotherapeutics through collaboratively recruiting the photoheating-mediated enhanced permeability and the hydrogel particle-assisted high drug retention, shedding new light on a "central-to-peripheral" drug pervasion and retention mechanism to destroy tumors completely. The fiber-optic chemotherapy strategy incorporates precise drug delivery, accurate controllability of drug release, high drug permeability and retention in tumor, low off-target rate, and real-time drug release and temperature feedback, performing a straightforward and precise photothermal-chemotherapy pathway. More than that, the proposed strategy holds tremendous promise to provide a revolutionized on-demand drug delivery platform for the highly efficient evaluation and screening of antitumor pharmaceuticals.  
        
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      Published:2024-10-15
    • Xutao Zhang,Fanlu Zhang,Ruixuan Yi,Naiyin Wang,Zhicheng Su,Mingwen Zhang,Bijun Zhao,Ziyuan Li,Jiangtao Qu,Julie M. Cairney,Yuerui Lu,Jianlin Zhao,Xuetao Gan,Hark Hoe Tan,Chennupati Jagadish,Lan Fu
      Vol. 13, Issue 10, Pages: 2405-2413(2024) DOI: 10.1038/s41377-024-01570-7
      Abstract:Highly integrated optoelectronic and photonic systems underpin the development of next-generation advanced optical and quantum communication technologies, which require compact, multiwavelength laser sources at the telecom band. Here, we report on-substrate vertical emitting lasing from ordered InGaAs/InP multi-quantum well core–shell nanowire array epitaxially grown on InP substrate by selective area epitaxy. To reduce optical loss and tailor the cavity mode, a new nanowire facet engineering approach has been developed to achieve controlled quantum well nanowire dimensions with uniform morphology and high crystal quality. Owing to the strong quantum confinement effect of InGaAs quantum wells and the successful formation of a vertical Fabry–Pérot cavity between the top nanowire facet and bottom nanowire/SiO2 mask interface, stimulated emissions of the EH11a/b mode from single vertical nanowires from an on-substrate nanowire array have been demonstrated with a lasing threshold of ~28.2 μJ cm−2 per pulse and a high characteristic temperature of ~128 K. By fine-tuning the In composition of the quantum wells, room temperature, single-mode lasing is achieved in the vertical direction across a broad near-infrared spectral range, spanning from 940 nm to the telecommunication O and C bands. Our research indicates that through a carefully designed facet engineering strategy, highly ordered, uniform nanowire arrays with precise dimension control can be achieved to simultaneously deliver thousands of nanolasers with multiple wavelengths on the same substrate, paving a promising and scalable pathway towards future advanced optoelectronic and photonic systems.  
        
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      Published:2024-10-15
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