Prediction of photothermal phase signatures from arbitrary plasmonic nanoparticles and experimental verification

Omry Blum; Natan T Shaked

doi:10.1038/lsa.2015.95

Go to Nature Website

Your Location：

Home >

Browse articles >

Prediction of photothermal phase signatures from arbitrary plasmonic nanoparticles and experimental verification

Original Articles

- Prediction of photothermal phase signatures from arbitrary plasmonic nanoparticles and experimental verification
- Light: Science & Applications Vol. 4, Issue 3, (2015)
- Affiliations：
  
  Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv 69978, Israel
- Author bio：
  
  NT Shaked, Email: nshaked@tau.ac.il
- Funds：
- DOI：10.1038/lsa.2015.95
  CLC：
- Published：2015-09，
  
  Published Online：13 April 2015，
  
  Received：17 December 2014，
  
  Revised：06 April 2015，
  
  Accepted：12 April 2015
- Accepted：
Scan QR Code
Blum, O. & Shaked, N. T. Prediction of photothermal phase signatures from arbitrary plasmonic nanoparticles and experimental verification. Light: Science & Applications, 4, e322 (2015).
DOI：

Blum, O. & Shaked, N. T. Prediction of photothermal phase signatures from arbitrary plasmonic nanoparticles and experimental verification. Light: Science & Applications, 4, e322 (2015). DOI： 10.1038/lsa.2015.95.

摘要

Abstract

We present a new approach for predicting spatial phase signals originating from photothermally excited metallic nanoparticles of arbitrary shapes and sizes. The heat emitted from such a nanoparticle affects the measured optical phase signal via changes in both the refractive index and thickness of the nanoparticle surroundings. Because these particles can be bio-functionalized to bind certain biological cell components

they can be used for biomedical imaging with molecular specificity

as new nanoscopy labels

and for photothermal therapy. Predicting the ideal nanoparticle parameters requires a model that computes the thermal and phase distributions around the particle

thereby enabling more efficient phase imaging of plasmonic nanoparticles and avoiding trial-and-error experiments while using unsuitable nanoparticles. The proposed nonlinear model is the first to enable the prediction of phase signatures from nanoparticles with arbitrary parameters. The model is based on a finite-volume method for geometry discretization and an implicit backward Euler method for solving the transient inhomogeneous heat equation

followed by calculation of the accumulative phase signal. To validate the model

we compared its results with experimental results obtained for gold nanorods of various concentrations

which we acquired using a custom-built wide-field interferometric phase microscopy system.

关键词

Keywords

digital holographic microscopyinterferometric imagingnanoparticlesphase measurementplasmonics

references

Link S, El-Sayed MA. Shape and size dependence of radiative, non-radiative and photothermal properties of gold nanocrystals.Int Rev Phys Chem2000;19: 409–453..

Huang XH, El-Sayed MA. Plasmonic photo-thermal therapy (PPTT).Alexandria J Med2011;47: 1–9..

Huang X, Jain PK, El-Sayed IH, El-Sayed MA. Determination of the minimum temperature required for selective photothermal destruction of cancer cells with the use of immunotargeted gold nanoparticles.Photochem Photobiol2006;82: 412–417..

Fixler D, Zalevsky Z. In vivo tumor detection using polarization and wavelength reflection characteristics of gold nanorods.Nano Lett2013;13: 6292–6296..

Richardson HH, Carlson MT, Tandler PJ, Hernandez P, Govorov AO. Experimental and theoretical studies of light-to-heat conversion and collective heating effects in metal nanoparticle solutions.Nano Lett2009;9: 1139–1146..

Volkov AN, Sevilla C, Zhigilei LV. Numerical modeling of short pulse laser interaction with Au nanoparticle surrounded by water.Appl Surf Science2007;253: 6394–6399..

Sassaroli E, Li KC, O'Neill BE. Numerical investigation of heating of a gold nanoparticle and the surrounding microenvironment by nanosecond laser pulses for nanomedicine applications.Phys Med Biol2009;54: 5541–5560..

Ekici O, Harrison RK, Durr NJ, Eversole DS, Lee Met al. Thermal analysis of gold nanorods heated with femtosecond laser pulses.J Phys D Appl Phys2008;41: 185501..

Au L, Zheng DS, Zhou F, Li ZY, Li XDet al. A quantitative study on the photothermal effect of immuno gold nanocages targeted to breast cancer cells.ACS Nano2008;2: 1645–1652..

Huang XH, El-Sayed IH, Qian W, El-Sayed MA. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods.J Am Chem Soc2006;128: 2115–2120..

Cognet L, Tardin C, Boyer D, Choquet D, Tamarat Pet al. Single metallic nanoparticle imaging for protein detection in cells.Proc Natl Acad Sci2003;100: 11350–11355..

Boyer D, Tamarat P, Maali A, Lounis B, Orrit M. Photothermal imaging of nanometer-sized metal particles among scatterers.Science2002;297: 1160–1163..

Skala MC, Crow MJ, Wax A, Izatt JA. Photothermal optical coherence tomography of epidermal growth factor receptor in live cells using immunotargeted gold nanospheres.Nano Lett2008;8: 3461–3467..

Adler DC, Huang SW, Huber R, Fujimoto JG. Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography.Opt Express2008;16: 4376–4393..

Turko NA, Peled A, Shaked NT. Wide-Field interferometric phase microscopy with molecular specificity using plasmonic nanoparticles.J Biomed Opt2013;18: 111414..

Dewhirst MW, Viglianti BL, Lora-Michiels M, Hanson M, Hoopes PJ. Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia.Int J Hyperthermia2003;19: 267–294..

Huang XH, Kang B, Qian W, Mackey MA, Chen PCet al. Comparative study of photothermolysis of cancer cells with nuclear-targeted or cytoplasm-targeted gold nanospheres: continuous wave or pulsed lasers.J Biomed Opt2010;15: 058002..

Link S, Mohamed MB, El-Sayed MA. Simulation of the optical absorption spectra of gold nanorods as a function of their aspect ratio and the effect of the medium dielectric constant.J Phys Chem B1999;103: 3073–3077..

Recktenwald GW. Finite-difference approximations to the heat equation. Class Notes 2004. Available athttp://www.f.kth.se/jjalap/numme/FDheat.pdfhttp://www.f.kth.se/jjalap/numme/FDheat.pdf.

Hoffman JD, Frankel S.Numerical Methods for Engineers and Scientists. 2nd ed. New York: CRC Press; 2001. pp 270–279.

Saad Y, Schultz MH. GMRES: a generalized minimal residual algorithm for solving nonsymmetric linear systems.SIAM J Sci Stat Comput1986;7: 856–869..

Murphy DB, Davidson MW.Fundamentals of Light Microscopy and Electronic Imaging. Hoboken, NJ: John Wiley&Sons; 2012.

Moran MJ, Shapiro HN, Boettner DD, Bailey MB.Fundamentals of Engineering Thermodynamics. Hoboken, NJ: John Wiley&Sons; 2010. pp817–818.

Schiebener P, Straub J, Sengers JM, Gallagher JS. Refractive index of water and steam as function of wavelength, temperature and density.J Phys Chem Ref Data1990;19: 677–717..

Harvey AH, Gallagher JS, Sengers JM. Revised formulation for the refractive index of water and steam as a function of wavelength, temperature and density.J Phys Chem Ref Data1998;27: 761–774..

Tucker-Schwartz JM, Meyer TA, Patil CA, Duvall CL, Skala MC. In vivo photothermal optical coherence tomography of gold nanorod contrast agents.Biomed Opt Express2012;3: 2881–2895..

Cuche E, Marquet P, Depeursinge C. Simultaneous amplitude-contrast and quantitative phase-contrast microscopy by numerical reconstruction of Fresnel off-axis holograms.Appl Opt1999;38: 6994–7001..

Girshovitz P, Shaked NT. Fast phase processing in off-axis holography using multiplexing with complex encoding and live-cell fluctuation map calculation in real-time.Opt Express, 2015;23: 8773–8787..

Turko N, Barnea I, Blum O, Korenstein R, Shaked NT. Detection and controlled depletion of cancer cells using photothermal phase microscopy.J Biophoton: doi:10.1002/jbio.201400095http://dx.doi.org/10.1002/jbio.201400095..

Baffou G, Quidant R, García de Abajo FJ. Nanoscale control of optical heating in complex plasmonic systems.ACS Nano2010;4: 709–716..

Zharov VP, Lapotko DO. Photothermal imaging of nanoparticles and cells.IEEE J Sel Top Quantum Electron2005;11: 733–751..

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Tuning the chemiluminescence of a luminol flow using plasmonic nanoparticles

Phase-sensitive plasmonic biosensor using a portable and large field-of-view interferometric microarray imager

Optical manipulation from the microscale to the nanoscale: fundamentals, advances and prospects

Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection

Beam switching and bifocal zoom lensing using active plasmonic metasurfaces

Related Author

Alina Karabchevsky

Ali Mosayyebi

Alexey V Kavokin

Filiz Yesilkoy

Roland A Terborg

Josselin Pello

Alexander A Belushkin

Yasaman Jahani

Related Institution

Electrooptical Engineering Unit and Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University, Beer-Sheva

Engineering Sciences Unit, Engineering and the Environment, University of Southampton

Department of Physics and Astronomy, University of Southampton

CNR-SPIN, Viale del Politecnico 1,- Rome

ICFO—Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, Castelldefels (Barcelona)

⁰