Focusing light into scattering media with ultrasound-induced field perturbation

Zhongtao Cheng; Lihong V. Wang

doi:10.1038/s41377-021-00605-7

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Focusing light into scattering media with ultrasound-induced field perturbation

Articles

- Focusing light into scattering media with ultrasound-induced field perturbation
- Light: Science & Applications Vol. 10, Issue 9, Pages: 1702-1713(2021)
- Affiliations：
  
  Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, Department of Electrical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA
- Author bio：
  
  Lihong V. Wang (LVW@caltech.edu)
- Funds：
- DOI：10.1038/s41377-021-00605-7
  CLC：
- Published：30 September 2021，
  
  Published Online：02 August 2021，
  
  Received：29 April 2021，
  
  Revised：16 July 2021，
  
  Accepted：20 July 2021
- Accepted：
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Cheng, Z. T. & Wang, L. V. Focusing light into scattering media with ultrasound-induced field perturbation. Light: Science & Applications, 10, 1702-1713 (2021).
DOI：

Cheng, Z. T. & Wang, L. V. Focusing light into scattering media with ultrasound-induced field perturbation. Light: Science & Applications, 10, 1702-1713 (2021). DOI： 10.1038/s41377-021-00605-7.

摘要

Abstract

Focusing light into scattering media

although challenging

is highly desirable in many realms. With the invention of time-reversed ultrasonically encoded (TRUE) optical focusing

acousto-optic modulation was demonstrated as a promising guidestar mechanism for achieving noninvasive and addressable optical focusing into scattering media. Here

we report a new ultrasound-assisted technique

ultrasound-induced field perturbation optical focusing

abbreviated as UFP. Unlike in conventional TRUE optical focusing

where only the weak frequency-shifted first-order diffracted photons due to acousto-optic modulation are useful

here UFP leverages the brighter zeroth-order photons diffracted by an ultrasonic guidestar as information carriers to guide optical focusing. We find that the zeroth-order diffracted photons

although not frequency-shifted

do have a field perturbation caused by the existence of the ultrasonic guidestar. By detecting and time-reversing the differential field of the frequency-unshifted photons when the ultrasound is alternately ON and OFF

we can focus light to the position where the field perturbation occurs inside the scattering medium. We demonstrate here that UFP optical focusing has superior performance to conventional TRUE optical focusing

which benefits from the more intense zeroth-order photons. We further show that UFP optical focusing can be easily and flexibly developed into double-shot realization or even single-shot realization

which is desirable for high-speed wavefront shaping. This new method upsets conventional thinking on the utility of an ultrasonic guidestar and broadens the horizon of light control in scattering media. We hope that it provides a more efficient and flexible mechanism for implementing ultrasound-guided wavefront shaping.

关键词

Keywords

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