Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region

Cheng-Wei Lu; Jing Fu; Xiu-Fen Liu; Zhi-Hua Cui; Wei-Wei Chen; Li Guo; Xiao-Lan Li; Yu Ren; Fei Shao; Li-Na Chen; Ji-Long Hao

doi:10.1038/s41377-023-01207-1

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Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region

Original Articles

- Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region
- Light: Science & Applications Vol. 12, Issue 9, Pages: 1757-1770(2023)
- Affiliations：
  
  1.Opthalmology Department, The First Hospital of Jilin University, Changchun 130021, China
  2.Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China
  3.College of New Energy and Environment, Jilin University, Changchun 130021, China
  4.China College of Biological and Agricultural Engineering, Jilin University, Changchun 130022, China
  5.Shenyang Institute of Atmospheric Environment, China Meteorological Administration, Shenyang 110166, China
- Author bio：
  
  Cheng-Wei Lu (lcwchina800@jlu.edu.cn)
  Wei-Wei Chen (chenweiwei@iga.ac.cn)
- Funds：
- DOI：10.1038/s41377-023-01207-1
  CLC：
- Published：30 September 2023，
  
  Published Online：27 July 2023，
  
  Received：17 January 2023，
  
  Revised：07 June 2023，
  
  Accepted：10 June 2023
- Accepted：
Scan QR Code
Lu, C. W. et al. Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region. Light: Science & Applications, 12, 1757-1770 (2023).
DOI：

Lu, C. W. et al. Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region. Light: Science & Applications, 12, 1757-1770 (2023). DOI： 10.1038/s41377-023-01207-1.

摘要

Abstract

The purpose of this study is to explore the associations among dry eye disease (DED)

air pollution

and meteorological conditions in the cold region of a northeastern Chinese metropolis (i.e.

Changchun). Data on ambient air pollutants and meteorological parameters as well as diagnosed DED outpatients during 2015–2021 were collected. The associations between DED and environmental factors were analysed at multiple time scales using various statistical methods (i.e.

correlation

regression and machine learning). Among the 10

809 DED patients (21

617 eyes) studied

64.60% were female and 35.40% were male. A higher frequency of DED was observed in March and April

followed by January

August and October. Individual and multiple factor models showed the positive importance of particles with aerodynamic diameters

10 μm (PM

)

carbon monoxide (CO)

and ozone (O

) among normal air pollutants and air pressure (AP)

air temperature (AT) and wind speed (WS) among normal meteorological parameters. Air pollutants (PM

nitrogen dioxide: NO

) and meteorological parameters (AT

AP) have combined impacts on DED occurrence. For the first time

we further explored the associations of detailed compon

ents of atmospheric particles and DED

suggesting potential emission sources

including spring dust from bare soil and roads and precursor pollutants of summer O

formation from vehicles and industry in Northeast China. Our results revealed the quantitative associations among air pollutants

meteorological conditions and DED outpatients in cold regions

highlighting the importance of coordinated policies in air pollution control and climate change mitigation.

关键词

Keywords

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