
无数据
1.College of Science, National University of Defense Technology, Changsha, China
2.Xi'an Satellite Control Center, Xi'an, China
3.School of Information and Electronics Engineering, Hunan City University, Yiyang, China
4.College of Electronic Science, National University of Defense Technology, Changsha, China
5.The School of Computer Science and Technology, Xidian University, Xi'an, China
6.Senior Department of Otolaryngology Head and Neck Surgery, the 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China
Wenjun Yi (yiwenjun@nudt.edu.cn)
Qiong Liu (joanlq@sina.com)
Xiujian Li (xjli@nudt.edu.cn)
Received:16 August 2024,
Revised:19 January 2025,
Accepted:2025-02-06,
Published Online:07 March 2025,
Published:30 April 2025
Scan QR Code
Yi, W. J. et al. Relay-projection microscopic telescopy. Light: Science & Applications, 14, 1143-1155 (2025).
Yi, W. J. et al. Relay-projection microscopic telescopy. Light: Science & Applications, 14, 1143-1155 (2025). DOI: 10.1038/s41377-025-01800-6.
The fundamental trade-off between spatial resolution and imaging distance poses a significant challenge for current imaging techniques
such as those used in modern biomedical diagnosis and remote sensing. Here
we introduce a new conceptual method for imaging dynamic amplitude-phase-mixed objects
termed relay-projection microscopic telescopy (rPMT)
which fundamentally challenges conventional light collection techniques by employing non-line-of-sight light collection through square-law relay-projection mechanisms. We successfully resolved tin
y
features measuring 2.76 μm
22.10 μm
and 35.08 μm for objects positioned at distances of 1019.0 mm
26.4 m
and 96.
0 m
respectively
from single-shot spatial power spectrum images captured on the relay screen; these results demonstrate that the resolution capabilities of rPMT significantly surpass the Abbe diffraction limit of the 25 mm-aperture camera lens at the respective distances
achieving resolution improvement factors of 7.9
25.4
and 58.2. The rPMT exhibits long-distance
wide-range
high-resolution imaging capabilities that exceed the diffraction limit of the camera lens and the focusing range limit
even when the objects are obscured by a scattering medium. The rPMT enables telescopic imaging from centimeters to beyond hundreds of meters with micrometer-scale resolution using simple devices
including a laser diode
a portable camera
and a diffusely reflecting whiteboard. Unlike contemporary high-resolution imaging techniques
our method does not require labeling reagents
wavefront modulation
synthetic receive aperture
or ptychography scanning
which significantly reduce the complexity of the imaging system and enhance the application practicality. This method holds particular promise for in-vivo label-free dynamic biomedical microscopic imaging diagnosis and remote surveillance of small objects.
Hell, S. W. Far-field optical nanoscopy. Science 316 , 1153–1158 (2007)..
Wang, P. et al. Far-field imaging of non-fluorescent species with subdiffraction resolution. Nat. Photonics 7 , 449–453 (2013)..
Sang, S. B. et al. Progress of new label-free techniques for biosensors: a review. Crit. Rev. Biotechnol. 36 , 465–481 (2016)..
Edrei, E. & Scarcelli, G. Optical imaging through dynamic turbid media using the Fourier-domain shower-curtain effect. Optica 3 , 71–74 (2016)..
Heintzmann, R. & Huser, T. Super-resolution structured illumination microscopy. Chem. Rev. 117 , 13890–13908 (2017)..
Schermelleh, L. et al. Super-resolution microscopy demystified. Nat. Cell Biol. 21 , 72–84 (2019)..
Shaked, N. T. et al. Label-free biomedical optical imaging. Nat. Photonics 17 , 1031–1041 (2023)..
Miao, J. W. et al. Extending the methodology of X-ray crystallography to allow imaging of micrometre-sized non-crystalline specimens. Nature 400 , 342–344 (1999)..
Huijts, J. et al. Broadband coherent diffractive imaging. Nat. Photonics 14 , 618–622 (2020)..
Liu, Y. Y. et al. High-resolution multi-wavelength lensless diffraction imag ing with adaptive dispersion correction. Opt. Express 29 , 7197–7209 (2021)..
Bertolotti, J. et al. Non-invasive imaging through opaque scattering layers. Nature 491 , 232–234 (2012)..
Katz, O. et al. Non-invasive single-shot imaging through scattering layers and around corners via speckle correlations. Nat. Photonics 8 , 784–790 (2014)..
Marcus, S., Colella, B. D. & Green, T. J. Solid-state laser synthetic aperture radar. Appl. Opt. 33 , 960–964 (1994)..
Lucke, R. L. et al. Synthetic Aperture Ladar (SAL): Fundamental Theory, Design Equations for a Satellite System, and Laboratory Demonstration. (Naval Research Laboratory, 2002).
Rodenburg, J. M. & Faulkner, H. M. L. A phase retrieval algorithm for shifting illumination. Appl. Phys. Lett. 85 , 4795–4797 (2004)..
Maiden, A. M. et al. Superresolution imaging via ptychography. J. Optical Soc. Am. A 28 , 604–6 12 (2011)..
Holloway, J. et al. SAVI: synthetic apertures for long-range, subdiffraction-limited visible imaging using Fourier ptychography. Sci. Adv. 3 , e1602564 (2017)..
Huang, Q. et al. Scatter ptychography. Print at https://arxiv.org/abs/2203.12561 https://arxiv.org/abs/2203.12561 (2022).
Pei, X. C., Shan, H. M. & Xie, X. S. Super-resolution imaging with large field of view for distant object through scattering media. Opt. Lasers Eng. 164 , 107502 (2023)..
Hell, S. W. & Wichmann, J. Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy. Opt. Lett. 19 , 780–782 (1994)..
Betzig, E. et al. Imaging intracellular fluorescent proteins at nanometer resolution. Science 313 , 1642–1645 (2006)..
Rust, M. J., Bates, M. & Zhuang, X. W. Sub-diffraction-limit imaging by stochastic optical reconstruct ion microscopy (STORM). Nat. Methods 3 , 793–796 (2006)..
Jungmann, R. et al. Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT. Nat. Methods 11 , 313–318 (2014)..
Candès, E. J., Li, X. D. & Soltanolkotabi, M. Phase retrieval from coded diffraction patterns. Appl. Comput. Harmonic Anal. 39 , 277–299 (2015)..
Zhang, F. C. et al. Phase retrieval by coherent modulation imaging. Nat. Commun. 7 , 13367 (2016)..
Nakamura, Y. et al. Lensless light-field imaging with fresnel zone aperture. ITE Tech. Rep. 40 , 7–8 (2016)..
Wu, Y. C. et al. WISH: wavefront imaging sensor with high resolution. Light Sci. Appl. 8 , 44 (2019)..
Zhang, H. et al. Near-field Fourier ptychography: super-resolution phase retrieval via speckle illumination. Opt. Express 27 , 7498–7512 (2019)..
Zuo, C. et al. Lensless phase microscopy and diffraction tomography with multi-angle and multi-wavelength illuminations using a LED matrix. Opt. Express 23 , 14314–14328 (2015)..
Ishizuka, K. & Allman, B. Phase measurement of atomic resolution image using transport of intensity equation. J. Electron Microsc. 54 , 191–197 (2005)..
Zuo, C. et al. Transport of intensity equation: a tutorial. Opt. Lasers Eng. 135 , 106187 (2020)..
Weaver, C. S. & Goodman, J. W. A technique for optically convolving two functions. Appl. Opt. 5 , 1248–1249 (1966)..
Yu, F. T. S. et al. Adaptive real-time pattern recognition using a liquid crystal TV based joint transform correlator. Appl. Opt. 26 , 1370–1372 (1987)..
Abbe, P. The relation of aperture and power in the microscope. J. R. Microsc. Soc. 2 , 300–309 (1882)..
Gerchberg, R. W. Phase determination from image and diffraction plane pictures in the electron microscope. Optik 34 , 275–284 (1971)..
Gerchberg, R. W. & Saxton, W. O. A practical algorithm for the determination of phase from image and diffraction plane pictures. Optik 35 , 237–246 (1972)..
Fienup, J. R. Reconstruction of an object from the modulus of its Fourier transform. Opt. Lett. 3 , 27–29 (1978)..
Fienup, J. R. Phase retrieval algorithms: a comparison. Appl. Opt. 21 , 2758–2769 (1982)..
Hofer, M. et al. Wide field fluorescence epi-microscopy behind a scattering medium enabled by speckle correlations. Opt. Express 26 , 9866–9881 (2018)..
Zhang, F. C. & Rodenburg, J. M. Phase retrieval based on wave-front relay and modulation. Phys. Rev. B 82 , 121104 (2010)..
Miller, D. A. B. Why optics needs thickness. Science 379 , 41–45 (2023)..
Mertens, T., Kautz, J. & Van Reeth, F. Exposure fusion: a simple and practical alternative to high dynamic range photography. Comput. Graph. Forum 28 , 161–171 (2009)..
Ma, K. D.&Wang, Z. Multi-exposure image fusion: a patch-wise approach. Proceedings of 2015IEEE International Conference on Image Processing. Quebec City, QC, Canada: IEEE, 1717–1721, 2015).
Feng, S. C. et al. Correlations and fluctuations of coherent wave transmission through disordered media. Phys. Rev. Lett. 61 , 834–837 (1988)..
Freund, I., Rosenbluh, M. & Feng, S. C. Memory effects in propagation of optical waves through disordered media. Phys. Rev. Lett. 61 , 2328–2331 (1988)..
Judkewitz, B. et al. Translation correlations in anisotropically scattering media. Nat. Phys. 11 , 684–689 (2015)..
Tang, W. S. et al. Single-shot coherent power-spectrum imaging of objects hidd en by opaque scattering media. Appl. Opt. 58 , 1033–1039 (2019)..
Williams, G. J. et al. Fresnel coherent diffractive imaging. Phys. Rev. Lett. 97 , 025506 (2006)..
Williams, G. J. et al. Fresnel coherent diffractive imaging: treatment and analysis of data. N. J. Phys. 12 , 035020 (2010)..
Fienup, J. R., Crimmins, T. R. & Holsztynski, W. Reconstruction of the support of an object from the support of its autocorrelation. J. Optical Soc. Am. 72 , 610–624 (1982)..
0
Views
0
Downloads
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621