Serial coherent diffraction imaging of dynamic samples based on inter-frame continuity

Pengju Sheng; Fucai Zhang

doi:10.1038/s41377-025-01860-8

Your Location：

Home >

Browse articles >

Serial coherent diffraction imaging of dynamic samples based on inter-frame continuity

Original Articles

- Serial coherent diffraction imaging of dynamic samples based on inter-frame continuity
- Light: Science & Applications Vol. 14, Issue 8, Pages: 2350-2359(2025)
- Affiliations：
  
  Department of Electronic and Electrical Engineering, Southern University of Science and Technology (SUSTech), Shenzhen, China
- Author bio：
  
  Fucai Zhang (zhangfc@sustech.edu.cn)
- Funds：
- DOI：10.1038/s41377-025-01860-8
  CLC：
- Received：05 August 2024，
  
  Revised：28 March 2025，
  
  Accepted：03 April 2025，
  
  Published Online：01 July 2025，
  
  Published：31 August 2025
- Accepted：
Scan QR Code
Sheng, P. J. & Zhang, F. C. Serial coherent diffraction imaging of dynamic samples based on inter-frame continuity. Light: Science & Applications, 14, 2350-2359 (2025).
DOI：

Sheng, P. J. & Zhang, F. C. Serial coherent diffraction imaging of dynamic samples based on inter-frame continuity. Light: Science & Applications, 14, 2350-2359 (2025). DOI： 10.1038/s41377-025-01860-8.

摘要

Abstract

Coherent diffraction imaging (CDI) provides lens-free imaging with diffraction-limited resolution and has become an important imaging modality at synchrotron facilities worldwide. The performance of current CDI approaches remains limited

particularly in their ability to handle dynamic samples or achieve consistent high-quality reconstructions. Here

we propose a novel coherent imaging approach for dynamic samples

which exploits the inter-frame continuity of the sample's local structures as an additional constraint in phasing a sequence of diffraction patterns. Our algorithm incorporates an adaptive similarity determination procedure

eliminating the requirement for invariant regions in the sample and ensuring broad applicability to diverse sample types. We demonstrated the feasibility of this technique through experiments on various dynamic samples

achieving high-fidelity reconstructions within a few hundred iterations. With the same simple setup as conventional CDI

high image quality

and the ability to separate the sample transmission from its illumination probe

our method has the potential to significantly advance X-ray imaging and electron microscopy techniques for dynamic sample analysis.

关键词

Keywords

references

Miao, J. W. et al. Beyond crystallography: diffractive imaging using coherent X-ray light sources. Science 348 , 530–535 (2015)..

Huijts, J. et al. Broadband coherent diffractive imaging. Nat. Photonics 14 , 618–622 (2020)..

Brändén, G. et al. Coherent diffractive imaging of microtubules using an X-ray laser. Nat. Commun. 10 , 2589 (2019)..

Wu, J. S. et al. Iterative phase retrieval without support. Opt. Lett. 29 , 2737–2739 (2004)..

Elser, V. Phase retrieval by iterated projections. J. Optical Soc. Am. A 20 , 40 (2003)..

Gerchberg, R. W. A practical algorithm for the determination of phase from image and diffraction plane pictures. Optik 35 , 237–246 (1972)..

Fienup, J. R. Reconstruction of an object from the modulus of its Fourier transform. Opt. Lett. 3 , 27–29 (1978)..

Fienup, J. R. Phase retrieval algorithms: a comparison. Appl. Opt. 21 , 2758–2769 (1982)..

Faulkner, H. M. L. & Rodenburg, J. M. Movable aperturelensless transmission microscopy: a novel phase retrieval algorithm. Phys. Rev. Lett. 93 , 023903 (2004)..

Maiden, A. M. & Rodenburg, J. M. An improved ptychographical phase retrieval algorithm for diffractive imaging. Ultramicroscopy 109 , 1256–1262 (2009)..

Hüe, F. et al. Extended ptychography in the transmission electron microscope: possibilities and limitations. Ultramicroscopy 111 , 1117–1123 (2011)..

Faulkner, H. M. L. & Rodenburg, J. M. Error tolerance of an iterative phase retrieval algorithm for moveable illumination microscopy. Ultramicroscopy 103 , 153–164 (2005)..

Chen, Z. et al. Electron ptychography achieves atomicresolution limits set by lattice vibrations. Science 372 , 826–831 (2021)..

Chen, Z. et al. Mixed-state electron ptychography enables sub-angstrom resolution imaging with picometer precision at low dose. Nat. Commun. 11 , 2994 (2020)..

Aidukas, T. et al. High-performance 4-nm-resolution X-ray tomography using burst ptychography. Nature 632 , 81–88 (2024)..

Zhou, L. Q. et al. Low-dose phase retrieval of biological specimens using cryo-electron ptychography. Nat. Commun. 11 , 2773 (2020)..

Pfeiffer, F. X-ray ptychography. Nat. Photonics 12 , 9–17 (2018)..

Beckers, M. et al. Drift correction in ptychographic diffractive imaging. Ultramicroscopy 126 , 44–47 (2013)..

Maiden, A. M. et al. An annealing algorithm to correct positioning errors in ptychography. Ultramicroscopy 120 , 64–72 (2012)..

Zhang, F. C. et al. Translation position determination in ptychographic coherent diffraction imaging. Opt. Express 21 , 13592–13606 (2013)..

Batey, D. J., Claus, D. & Rodenburg, J. M. Information multiplexing in ptychography. Ultramicroscopy 138 , 13–21 (2014)..

Karl, R. et al. Spatial, spectral, and polarization multiplexed ptychography. Opt. Express 23 , 30250–30258 (2015)..

Thibault, P. & Menzel, A. Reconstructing state mixtures from diffraction measurements. Nature 494 , 68–71 (2013)..

Clark, J. N. et al. Dynamic imaging using ptychography. Phys. Rev. Lett. 112 , 113901 (2014)..

Huang, X. J. et al. Fly-scan ptychography. Sci. Rep. 5 , 9074 (2015)..

Sidorenko, P. & Cohen, O. Single-shot ptychography. Optica 3 , 9–14 (2016)..

Zhang, F. C. & Rodenburg, J. M. Phase retrieval based on wave-front relay and modulation. Phys. Rev. B 82 , 121104 (2010)..

Zhang, F. C. et al. Phase retrieval by coherent modulation imagi ng. Nat. Commun. 7 , 13367 (2016)..

Lin, H. X. et al. Broadband coherent modulation imaging with no knowledge of the illumination spectrum distribution. Opt. Lett. 48 , 3977–3980 (2023)..

Wang, B. Y., He, Z. F. & Zhang, F. C. Coherent modulation imaging using unknown modulators. Opt. Express 29 , 30035–30044 (2021)..

Tao, X. L. et al. Spatially correlated coherent diffractive imaging method. Appl. Opt. 57 , 6527–6533 (2018)..

Yuan, Z. Y. & Wang, H. X. Phase retrieval with background information. Inverse Probl. 35 , 054003 (2019)..

Hinsley, G. N. et al. Dynamic coherent diffractive imaging using unsupervised identification of spatiotemporal constraints. Opt. Express 28 , 36862–36872 (2020)..

Lo, Y. H. et al. In situ coherent diffractive imaging. Nat. Commun. 9 , 1826 (2018)..

Sun, M. et al. Spacetime Fourier ptychography for in vivo quantitati ve phase imaging. Optica 11 , 1250–1260 (2024)..

Cao, L. H. & Gao, Y. C. Motion-resolved, reference-free holographic imaging via spatiotemporally regularized inversion. Optica 11 , 32–41 (2024)..

Nayer, S., Vaswani, N.&Eldar, Y. C. Low-rank phase retrieval. In Proceedings of the IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP). New Orleans, LA, USA: 4446–4450 (IEEE, 2017).

Fienup, J. R. Reconstruction of a complex-valued object from the modulus of its Fourier transform using a support constraint. J. Optical Soc. Am. A 4 , 118–123 (1987)..

Hinsley, G. N., Kewish, C. M. & van Riessen, G. A. Dynamic and spectral coherent diffractive imaging. AIP Conf. Proc. 2990 , 040015 (2023).

Marchesini, S. et al. X-ray image reconstruction from a diffraction pattern alone. Phys. Rev. B 68 , 140101 (2003)..

Petrakis, S. et al. Coherent XUV multispectral diffraction imaging in the microscale. Appl. Sci. 12 , 10592 (2022)..

Malm, E., Fohtung, E. & Mikkelsen, A. Multi-wavelength phase retrieval for coherent diffractive imaging. Opt. Lett. 46 , 13–16 (2021)..

Abbey, B. et al. Lensless imaging using broadband X-ray sources. Nat. Photonics 5 , 420–424 (2011)..

Nellist, P. D. & Rodenburg, J. M. Beyond the conventional information limit: the relevant coherence function. Ultramicroscopy 54 , 61–74 (1994)..

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰