Efficient luminescent stable Chichibabin diradicaloid for near-infrared imaging and photothermal therapy

Ting Liu; Zihao Zhu; Shengjie Wang; Li Shen; Alim Abdurahman; Xiaomin Liu; Geyu Lu

doi:10.1038/s41377-025-01993-w

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Efficient luminescent stable Chichibabin diradicaloid for near-infrared imaging and photothermal therapy

Original Articles

- Efficient luminescent stable Chichibabin diradicaloid for near-infrared imaging and photothermal therapy
- Light: Science & Applications Vol. 14, Issue 10, Pages: 3092-3101(2025)
- Affiliations：
  
  1.State Key Laboratory of Integrated Optoelectronics, JLU Region, College of Electronic Science and Engineering, Jilin University, Qianjin Avenue 2699, Changchun 130012, China
  2.College of Chemical Engineering and Environmental Chemistry, Weifang University, Weifang 261061, China
- Author bio：
  
  Alim Abdurahman (alim@jlu.edu.cn)
  Xiaomin Liu (xiaominliu@jlu.edu.cn)
  Geyu Lu (lugy@jlu.edu.cn)
- Funds：
- DOI：10.1038/s41377-025-01993-w
  CLC：
- Received：23 May 2025，
  
  Revised：2025-07-26，
  
  Accepted：27 July 2025，
  
  Published Online：26 August 2025，
  
  Published：31 October 2025
- Accepted：
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Liu, T. et al. Efficient luminescent stable Chichibabin diradicaloid for near-infrared imaging and photothermal therapy. Light: Science & Applications, 14, 3092-3101 (2025).
DOI：

Liu, T. et al. Efficient luminescent stable Chichibabin diradicaloid for near-infrared imaging and photothermal therapy. Light: Science & Applications, 14, 3092-3101 (2025). DOI： 10.1038/s41377-025-01993-w.

摘要

Abstract

Diradicaloids have garnered significant attention due to their unique electronic

photophysical properties and potential applications in functional materials. Characterized by a narrow band gap and near-infrared (NIR) absorption

diradicaloids are promising candidates for NIR-guided photothermal therapy. However

they are often unstable and exhibit non-emissive properties due to high chemical reactivity and very efficient internal conversion. Herein

we report a remarkably stable Chichibabin diradicaloid

TT-CzPh

which exhibits NIR luminescence (λ

= 821 nm) with an efficient photoluminescence quantum yield (PLQY) of 6.4%. Surprisingly

TT-CzPh not only exhibits excellent NIR imaging but also has a very high photothermal conversion efficiency (PCE) of 87.5%. In vivo experim

ents with TT-CzPh nanoparticles demonstrated their effectiveness in tumor photoablation guided by NIR imaging. This work not only advances the development of stable

efficient luminescent Chichibabin’s hydrocarbons but also opens new avenues for bioimaging and cancer phototherapy applications.

关键词

Keywords

references

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