Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography

Xosé Luís Deán-Ben; Daniel Razansky

doi:10.1038/lsa.2014.18

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Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography

Original Articles

- Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography
- Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography
- LSA 2014年3卷第1期
- Affiliations：
  
  Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich, 85764 Neuherberg, Germany
- Author bio：
  
  Dr D Razansky, Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich, Ingolstädter Landstrabe 1, 85764 Neuherberg, Germany E-mail: dr@tum.de
- Funds：
- DOI：10.1038/lsa.2014.18
  中图分类号：
- 纸质出版日期：2014-03，
  
  网络出版日期：2014-01-31，
  
  收稿日期：2013-05-10，
  
  修回日期：2013-09-24，
  
  录用日期：2013-09-27
- Accepted：
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Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography[J]. LSA, 2014,3(1).

Deán-Ben, X. L. & Razansky, D. Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography. Light: Science & Applications, 3, e137 (2014).
Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography[J]. LSA, 2014,3(1). DOI： 10.1038/lsa.2014.18.

Deán-Ben, X. L. & Razansky, D. Adding fifth dimension to optoacoustic imaging: volumetric time-resolved spectrally enriched tomography. Light: Science & Applications, 3, e137 (2014). DOI： 10.1038/lsa.2014.18.

摘要

Abstract

Optoacoustics provides a unique set of capabilities for bioimaging

associated with the intrinsic combination of ultrasound- and light-related advantages

such as high spatial and temporal resolution as well as powerful spectrally enriched imaging contrast in biological tissues. We demonstrate here

for the first time

the acquisition

processing and visualization of five-dimensional optoacoustic data

thus offering unparallel imaging capacities among the current bioimaging modalities. The newly discovered performance is enabled by simultaneous volume

tric detection and processing of multispectral data and is further showcased here by attaining time-resolved volumetric blood oxygenation maps in deep human vessels and real-time tracking of contrast agent distribution in a murine model

in vivo

关键词

Keywords

biophotonicsmultispectraloptoacoustic imagingphotoacoustic tomography

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