Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing

Ting-Hui Xiao; Yuqi Zhou; Keisuke Goda

doi:10.1038/s41377-023-01199-y

Go to Nature Website

Your Location：

Home >

Browse articles >

Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing

News & Views

- Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing
- Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing
- LSA 2023年12卷第8期页码：1439-1440
- Affiliations：
  
  1.Henan Key Laboratory of Diamond Optoelectronic Materials and Devices, School of Physics and Microelectronics, Zhengzhou University, Zhengzhou 450052, China
  2.Institute of Quantum Materials and Physics, Henan Academy of Sciences, Zhengzhou 450046, China
  3.Department of Chemistry, School of Science, The University of Tokyo, Tokyo 113-0033, Japan
  4.Institute of Technological Sciences, Wuhan University, Wuhan 430072, China
  5.Department of Bioengineering, University of California, Los Angeles, CA 90095, USA
- Author bio：
  
  Keisuke Goda (goda@chem.s.u-tokyo.ac.jp)
- Funds：
- DOI：10.1038/s41377-023-01199-y
  中图分类号：
- 纸质出版日期：2023-08-31，
  
  网络出版日期：2023-06-27，
- Accepted：
Scan QR Code
Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing[J]. LSA, 2023,12(8):1439-1440.

Xiao, T. H., Zhou, Y.Q. & Goda K. Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing. Light: Science & Applications, 12, 1439-1440 (2023).
Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing[J]. LSA, 2023,12(8):1439-1440. DOI： 10.1038/s41377-023-01199-y.

Xiao, T. H., Zhou, Y.Q. & Goda K. Unlocking the secrets of the invisible world: incredible deep optical imaging through in-silico clearing. Light: Science & Applications, 12, 1439-1440 (2023). DOI： 10.1038/s41377-023-01199-y.

摘要

Abstract

In-silico clearing enables deep optical imaging of biological samples by correcting image blur caused by scattering and aberration. This breakthrough method offers researchers unprecedented insights into three-dimensional biological systems

with enormous potential for advancing biology and medicine to better understand living organisms and human health.

关键词

Keywords

references

Yoon, S. et al. Deep optical imaging within complex scattering media.Nat. Rev. Phys.2, 141–158 (2020)..

Badon, A. et al. Distortion matrix concept for deep optical imaging in scattering media.Sci. Adv.6, eaay7170 (2020)..

Chowdhury, S. et al. High-resolution 3D refractive index microscopy of multiple-scattering samples from intensity images.Optica6, 1211–1219 (2019)..

Lim, J. et al. High-fidelity optical diffraction tomography of multiple scattering samples.Light Sci. Appl.8, 82 (2019)..

Kang, S. et al. Imaging deep within a scattering medium using collective accumulation of single-scattered waves.Nat. Photonics9, 253–258 (2015)..

Mikami, H. et al. Ultrafast confocal fluorescence microscopy beyond the fluorescence lifetime limit.Optica5, 117–126 (2018)..

Huang, D. et al. Optical coherence tomography.Science254, 1178–1181 (1991)..

Booth, M. J. Adaptive optical microscopy: the ongoing quest for a perfect image.Light Sci. Appl.3, e165 (2014)..

Ji, N. Adaptive optical fluorescence microscopy.Nat. Methods14, 374–380 (2017)..

Yasuhiko, O.&Takeuchi, K. In-silico clearing approach for deep refractive index tomography by partial reconstruction and wave-backpropagation.Light Sci. Appl.12, 101 (2023)..

Scholler, J. et al. Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids.Light Sci. Appl.9, 140 (2020)..

Nishikawa, M. et al. Massive image-based single-cell profiling reveals high levels of circulating platelet aggregates in patients with COVID-19.Nat. Commun.12, 7135 (2021)..

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据