Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region

Cheng-Wei Lu; Jing Fu; Xiu-Fen Liu; Zhi-Hua Cui; Wei-Wei Chen; Li Guo; Xiao-Lan Li; Yu Ren; Fei Shao; Li-Na Chen; Ji-Long Hao

doi:10.1038/s41377-023-01207-1

Go to Nature Website

Your Location：

Home >

Browse articles >

Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region

Original Articles

- Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region
- Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region
- LSA 2023年12卷第9期页码：1757-1770
- Affiliations：
  
  1.Opthalmology Department, The First Hospital of Jilin University, Changchun 130021, China
  2.Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China
  3.College of New Energy and Environment, Jilin University, Changchun 130021, China
  4.China College of Biological and Agricultural Engineering, Jilin University, Changchun 130022, China
  5.Shenyang Institute of Atmospheric Environment, China Meteorological Administration, Shenyang 110166, China
- Author bio：
  
  Cheng-Wei Lu (lcwchina800@jlu.edu.cn)
  Wei-Wei Chen (chenweiwei@iga.ac.cn)
- Funds：
- DOI：10.1038/s41377-023-01207-1
  中图分类号：
- 纸质出版日期：2023-09-30，
  
  网络出版日期：2023-07-27，
  
  收稿日期：2023-01-17，
  
  修回日期：2023-06-07，
  
  录用日期：2023-06-10
- Accepted：
Scan QR Code
Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region[J]. LSA, 2023,12(9):1757-1770.

Lu, C. W. et al. Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region. Light: Science & Applications, 12, 1757-1770 (2023).
Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region[J]. LSA, 2023,12(9):1757-1770. DOI： 10.1038/s41377-023-01207-1.

Lu, C. W. et al. Impacts of air pollution and meteorological conditions on dry eye disease among residents in a northeastern Chinese metropolis: a six-year crossover study in a cold region. Light: Science & Applications, 12, 1757-1770 (2023). DOI： 10.1038/s41377-023-01207-1.

摘要

Abstract

The purpose of this study is to explore the associations among dry eye disease (DED)

air pollution

and meteorological conditions in the cold region of a northeastern Chinese metropolis (i.e.

Changchun). Data on ambient air pollutants and meteorological parameters as well as diagnosed DED outpatients during 2015–2021 were collected. The associations between DED and environmental factors were analysed at multiple time scales using various statistical methods (i.e.

correlation

regression and machine learning). Among the 10

809 DED patients (21

617 eyes) studied

64.60% were female and 35.40% were male. A higher frequency of DED was observed in March and April

followed by January

August and October. Individual and multiple factor models showed the positive importance of particles with aerodynamic diameters

10 μm (PM

)

carbon monoxide (CO)

and ozone (O

) among normal air pollutants and air pressure (AP)

air temperature (AT) and wind speed (WS) among normal meteorological parameters. Air pollutants (PM

nitrogen dioxide: NO

) and meteorological parameters (AT

AP) have combined impacts on DED occurrence. For the first time

we further explored the associations of detailed compon

ents of atmospheric particles and DED

suggesting potential emission sources

including spring dust from bare soil and roads and precursor pollutants of summer O

formation from vehicles and industry in Northeast China. Our results revealed the quantitative associations among air pollutants

meteorological conditions and DED outpatients in cold regions

highlighting the importance of coordinated policies in air pollution control and climate change mitigation.

关键词

Keywords

references

Kim, Y. et al. Different adverse effects of air pollutants on dry eye disease: Ozone, PM2.5, and PM10.Environ. Pollut.265, 115039 (2020)..

Mo, Z. et al. Impacts of air pollution on dry eye disease among residents in Hangzhou, China: a case-crossover study.Environ. Pollut.246, 183–189 (2019)..

Liu, Z. G. Paying attention to the expert consensus on dry eye to standardize and promote the clinical diagnosis and treatment of dry eye.Chin. J. Ophthalmol.56, 726–729 (2020)..

Farrand, K. F. et al. Prevalence of diagnosed dry eye disease in the united states among adults aged 18 years and older.Am. J. Ophthalmol.182, 90–98 (2017)..

Jie, Y. et al. Prevalence of dry eye among adult Chinese in the Beijing Eye study.Eye23, 688–693 (2009)..

Lee, A. J. et al. Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia.Br. J. Ophthalmol.86, 1347–1351 (2002)..

Lekhanont, K. et al. Prevalence of dry eye in Bangkok, Thailand.Cornea25, 1162–1167 (2006)..

Lin, P. Y. et al. Prevalence of dry eye among an elderly Chinese population in Taiwan: the Shihpai Eye Study.Ophthalmology110, 1096–1101 (2003)..

Schaumberg, D. A. et al. Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies.Arch. Ophthalmol.127, 763–768 (2009)..

Schaumberg, D. A. et al. Prevalence of dry eye syndrome among US women.Am. J. Ophthalmol.136, 318–326 (2003)..

Stapleton, F. et al. TFOS DEWS Ⅱ epidemiology report.Ocul. Surf.15, 334–365 (2017)..

Yu, J. H., Asche, C. V.&Fairchild, C. J. The economic burden of dry eye disease in the United States: a decision tree analysis.Cornea30, 379–387 (2011)..

Galor, A. et al. Environmental factors affect the risk of dry eye syndrome in a United States veteran population.Ophthalmology121, 972–973. e1 (2014)..

Guo, B. et al. Prevalence of dry eye disease in Mongolians at high altitude in China: the Henan eye study.Ophthalmic Epidemiol.17, 234–241 (2010)..

Sahai, A.&Malik, P. Dry eye: prevalence and attributable risk factors in a hospital-based population.Indian J. Ophthalmol.53, 87–91 (2005)..

Zhang, Q. et al. Transboundary health impacts of transported global air pollution and international trade.Nature543, 705–709 (2017)..

Song, J. et al. Acute effects of ambient particulate matter pollution on hospital admissions for mental and behavioral disorders: A time-series study in Shijiazhuang, China.Sci. Total Environ.636, 205–211 (2018)..

Hwang, S. H. et al. Potential importance of ozone in the association between outdoor air pollution and dry eye disease in South Korea.JAMA Ophthalmol.134, 503–510 (2016)..

Mu, J. F. et al. Associations between air pollution exposure and daily pediatric outpatient visits for dry eye disease: a time-series study in Shenzhen, China.Int. J. Public Health66, 1604235 (2021)..

Abusharha, A. A.&Pearce, E. I. The effect of low humidity on the human tear film.Cornea32, 429–434 (2013)..

Berg, E. J. et al. Climatic and environmental correlates ofdry eye disease severity: a report from the dry eye assessment and management (DREAM) study.Transl. Vis. Sci. Technol.9, 25 (2020)..

Chen, W. W. et al. Spatial and temporal characteristics of air quality and cause analysis of heavy pollution in Northeast China.Environ. Sci.40, 4810–4823 (2019)..

The facts, impacts, and countermeasures of climate change in the Northeast region. Liaoning, China: Climate Center of Meteorological Administration.https://baijiahao.baidu.com/s?id=1714733994285729380&wfr=spider&for=pchttps://baijiahao.baidu.com/s?id=1714733994285729380&wfr=spider&for=pc(2021).

Li, X. M. et al. Air pollution during the winter period and respiratory tract microbial imbalance in a healthy young population in Northeastern China.Environ. Pollut.246, 972–979 (2019)..

Hao, R. et al. Impact of air pollution on the ocular surface and tear cytokine levels: a multicenter prospective cohort study.Front. Med.9, 909330 (2022)..

Song, S. J. et al. New application for assessment of dry eye syndrome induced by particulate matter exposure.Ecotoxicol. Environ. Saf.205, 111125 (2020)..

Tan, G. et al. Air pollutant particulate matter 2.5 induces dry eye syndrome in mice.Sci. Rep.8, 17828 (2018)..

Aneja, V. P., Schlesinger, W. H.&Erisman, J. W. Effects of agriculture upon the air quality and climate: research, policy, and regulations.Environ. Sci. Technol.43, 4234–4240 (2009)..

Nordstrom, K. F.&Hotta, S. Wind erosion from cropland in the USA: a review of problems, solutions and prospects.Geoderma121, 157–167 (2004)..

Fu, J. et al. High-resolution inventory of emissions of atmospheric PM10from agricultural tillage and harvesting operations in China: historical trend, spatio-temporality, and optimization methodology.Air Qual., Atmosphere Health15, 853–865 (2022)..

Yang, Q. et al. Effects of fine particulate matter on the ocular surface: an in vitro and in vivo study.Biomed. Pharmacother.117, 109177 (2019)..

Chen, W. W. et al. Typical atmospheric haze during crop harvest season in northeastern China: a case in the Changchun region.J. Environ. Sci.54, 101–113 (2017)..

Lee, H. et al. Effects of ozone exposure on the ocular surface.Free Radic. Biol. Med.63, 78–89 (2013)..

Chung, C. J. et al. Exposure to ambient NO2increases the risk of Dry Eye syndrome in females: an 11-year population-based study.Int. J. Environ. Res. Public Health18, 6860 (2021)..

Wang, H. Y. et al. Insight into ozone profile climatology over northeast China from aircraft measurement and numerical simulation.Sci. Total Environ.785, 147308 (2021)..

Lu, C. W. et al. Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China.Light Sci. Appl.10, 190 (2021)..

Youn, J. S. et al. Prediction model for dry eye syndrome incidence rate using air pollutants and meteorological factors in South Korea: analysis of sub-region deviations.Int. J. Environ. Res. Public Health17, 4969 (2020)..

Versura, P. et al. Subjective discomfort symptoms are related to low corneal temperature in patients with evaporative dry eye.Cornea34, 1079–1085 (2015)..

Abusharha, A. A., Pearce, E. I.&Fagehi, R. Effect of ambient temperature on the human tear film.Eye Contact Lens: Sci. Clin. Pract.42, 308–312 (2016)..

Borchman, D. et al. Factors affecting evaporation rates of tear film components measured in vitro.Eye Contact Lens: Sci. Clin. Pract.35, 32–37 (2009)..

Willmann, G. et al. Exposure to high altitude alters tear film osmolarity and breakup time.High. Alt. Med. Biol.15, 203–207 (2014)..

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据