Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging

James A. Winkelmann; Aya Eid; Graham Spicer; Luay M. Almassalha; The-Quyen Nguyen; Vadim Backman

doi:10.1038/s41377-018-0117-7

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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging

Letters

- Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging
- Light: Science & Applications Vol. 8, Issue 1, Pages: 13-21(2019)
- Affiliations：
  
  1.Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA
  2.Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, 60208, USA
- Author bio：
  
  Vadim Backman (v-backman@northwestern.edu)
- Funds：
- DOI：10.1038/s41377-018-0117-7
  CLC：
- Published：2019，
  
  Published Online：16 January 2019，
  
  Received：25 June 2018，
  
  Revised：14 December 2018，
  
  Accepted：15 December 2018
- Accepted：
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Winkelmann, J. A. et al. Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. Light: Science & Applications, 8, 13-21 (2019).
DOI：

Winkelmann, J. A. et al. Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging. Light: Science & Applications, 8, 13-21 (2019). DOI： 10.1038/s41377-018-0117-7.

摘要

Abstract

Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method

which enables lymphatic vessel

blood

and tissue discrimination.

关键词

Keywords

references

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