Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras

David Knez; Adam M. Hanninen; Richard C. Prince; Eric O. Potma; Dmitry A. Fishman

doi:10.1038/s41377-020-00369-6

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Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras

Article

- Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras
- Light: Science & Applications Vol. 9, Issue 4, Pages: 1218-1227(2020)
- Affiliations：
  
  1.Department of Chemistry, University of California, Irvine, CA 92697, USA
  2.Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA
- Author bio：
  
  Eric O. Potma (epotma@uci.edu)
  Dmitry A. Fishman (dmitryf@uci.edu)
- Funds：
- DOI：10.1038/s41377-020-00369-6
  CLC：
- Published：2020，
  
  Published Online：20 July 2020，
  
  Received：30 March 2020，
  
  Revised：30 June 2020，
  
  Accepted：08 July 2020
- Accepted：
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Knez, D. et al. Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras. Light: Science & Applications, 9, 1218-1227 (2020).
DOI：

Knez, D. et al. Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras. Light: Science & Applications, 9, 1218-1227 (2020). DOI： 10.1038/s41377-020-00369-6.

摘要

Abstract

Chemical imaging based on mid-infrared (MIR) spectroscopic contrast is an important technique with a myriad of applications

including biomedical imaging and environmental monitoring. Current MIR cameras

however

lack performance and are much less affordable than mature Si-based devices

which operate in the visible and near-infrared regions. Here

we demonstrate fast MIR chemical imaging through non-degenerate two-photon absorption (NTA) in a standard Si-based charge-coupled device (CCD). We show that wide-field MIR images can be obtained at 100 ms exposure times using picosecond pulse energies of only a few femtojoules per pixel through NTA directly on the CCD chip. Because this on-chip approach does not rely on phase matching

it is alignment-free and does not necessitate complex postprocessing of the images. We emphasize the utility of this technique through chemically selective MIR imaging of polymers and biological samples

including MIR videos of moving targets

physical processes and live nematodes.

关键词

Keywords

references

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