Review of biosensing with whispering-gallery mode lasers

Nikita Toropov; Gema Cabello; Mariana P. Serrano; Rithvik R. Gutha; Matías Rafti; Frank Vollmer

doi:10.1038/s41377-021-00471-3

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Review of biosensing with whispering-gallery mode lasers

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- Review of biosensing with whispering-gallery mode lasers
- Light: Science & Applications Vol. 10, Issue 3, Pages: 352-370(2021)
- Affiliations：
  
  1.Department of Physics and Astronomy, Living Systems Institute, University of Exeter, Exeter EX4 4QD, UK
  2.Departamento de Química, Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas, Universidad Nacional de La Plata, La Plata 1900, Argentina
- Author bio：
  
  Nikita Toropov (n.toropov@exeter.ac.uk)
  Frank Vollmer (f.vollmer@exeter.ac.uk)
- Funds：
- DOI：10.1038/s41377-021-00471-3
  CLC：
- Published：31 March 2021，
  
  Published Online：26 February 2021，
  
  Received：25 August 2020，
  
  Revised：04 January 2021，
  
  Accepted：09 January 2021
- Accepted：
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Toropov, N. et al. Review of biosensing with whispering-gallery mode lasers. Light: Science & Applications 10, 352-370 (2021).
DOI：

Toropov, N. et al. Review of biosensing with whispering-gallery mode lasers. Light: Science & Applications 10, 352-370 (2021). DOI： 10.1038/s41377-021-00471-3.

摘要

Abstract

Lasers are the pillars of modern optics and sensing. Microlasers based on whispering-gallery modes (WGMs) are miniature in size and have excellent lasing characteristics suitable for biosensing. WGM lasers have been used for label-free detection of single virus particles

detection of molecular electrostatic changes at biointerfaces

and barcode-type live-cell tagging and tracking. The most recent advances in biosensing with WGM microlasers are described in this review. We cover the basic concepts of WGM resonators

the integration of gain media into various active WGM sensors and devices

and the cutting-edge advances in photonic devices for micro- and nanoprobing of biological samples that can be integrated with WGM lasers.

关键词

Keywords

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