Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China

Cheng-Wei Lu; Jing Fu; Xiu-Fen Liu; Wei-Wei Chen; Ji-Long Hao; Xiao-Lan Li; Om Prakash Pant

doi:10.1038/s41377-021-00630-6

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Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China

Articles

- Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China
- Light: Science & Applications Vol. 10, Issue 11, Pages: 2128-2142(2021)
- Affiliations：
  
  1.The Department of Ophthalmology, The First Hospital of Jilin University, Changchun, 130021, China
  2.Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, 130102, China
  3.Institute of Atmospheric Environment, China Meteorological Administration, Shenyang, 110166, China
  4.Dhangadhi Netralaya Eye Hospital, Dhangadhi, 3, Kailali, Nepal
- Author bio：
  
  Cheng-Wei Lu (lcwchina800@jlu.edu.cn)
  Wei-Wei Chen (chenweiwei@iga.ac.cn)
- Funds：
- DOI：10.1038/s41377-021-00630-6
  CLC：
- Published：30 November 2021，
  
  Published Online：17 September 2021，
  
  Received：16 May 2021，
  
  Revised：25 August 2021，
  
  Accepted：02 September 2021
- Accepted：
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Lu, C. W. et al. Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China. Light: Science & Applications, 10, 2128-2142 (2021).
DOI：

Lu, C. W. et al. Air pollution and meteorological conditions significantly contribute to the worsening of allergic conjunctivitis: a regional 20-city, 5-year study in Northeast China. Light: Science & Applications, 10, 2128-2142 (2021). DOI： 10.1038/s41377-021-00630-6.

摘要

Abstract

This study is the first to explore the potential associations among allergic conjunctivitis (AC)

air pollution

and meteorological conditions in Northeast China. Data of meteorology

ambient atmospheric pollutants

and the incidence of allergic conjunctivitis (IAC) in prefecture-level cities between the years 2014 and 2018 are analyzed. The results show an increasing trend in the AC of average gro

wth rate per annum 7.6%

with the highest incidence in the provincial capitals. The IAC is positively correlated with atmospheric pollutants (i.e.

2.5

and O

) and meteorological factors (i.e.

air temperature and wind speed)

but negatively correlated with relative humidity. These results suggest that the IAC is directly proportional to pollution level and climatic conditions

and also the precedence of air pollution. We have further obtained the threshold values of atmospheric pollutants concentration and meteorological factors

a turning point above which more AC may be induced. Compared with the air quality standard advised by China and the World Health Organization (WHO)

both thresholds of PM

(70 μg m

−3

) and PM

2.5

(45 μg m

−3

) are higher than current standards and pose a less environmental risk for the IAC. SO

threshold (23 μg m

−3

) is comparable to the WHO standard and significantly lower than that of China's

indicating greater environmental risks in China. Both thresholds of NO

(27 μg m

−3

) and O

(88 μg m

−3

) are below current standards

indicating that they are major environmental risk factors for the IAC. Our findings highlight the importance of atmospheric environmental protection and reference for health-based amendment.

关键词

Keywords

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