Versatile chip-based nanoscopy becomes ready for histopathology assessment

Martin Lopez-Garcia

doi:10.1038/s41377-022-00781-0

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Versatile chip-based nanoscopy becomes ready for histopathology assessment

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- Versatile chip-based nanoscopy becomes ready for histopathology assessment
- Light: Science & Applications Vol. 11, Issue 5, Pages: 730-732(2022)
- Affiliations：
  
  Natural and Artificial Photonic Structures Group, International Iberian Nanotechnology Laboratory, Braga, 4715-330, Portugal
- Author bio：
  
  Martin Lopez-Garcia (martin.lopez@inl.int)
- Funds：
- DOI：10.1038/s41377-022-00781-0
  CLC：
- Published：31 May 2022，
  
  Published Online：07 April 2022，
- Accepted：
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Lopez-Garcia, M. Versatile chip-based nanoscopy becomes ready for histopathology assessment. Light: Science & Applications 11, 730-732 (2022).
DOI：

Lopez-Garcia, M. Versatile chip-based nanoscopy becomes ready for histopathology assessment. Light: Science & Applications 11, 730-732 (2022). DOI： 10.1038/s41377-022-00781-0.

摘要

Abstract

Nanoscopy is a mature technology used routinely in life science to obtain images well below the optical diffraction limit. But the use of nanoscopy in histopathology assessment is very limited mostly due to the low throughput of traditional nanoscopic techniques. So far

Chip-nanoscopy

nanoscopy in which sample illumination is performed by an integrated photonic chip instead of bulk optics

has been shown to provide an enhanced field of view and throughput for cell biology. Now

a new development shows that chip-nanoscopy also offers interesting progress for the study of histological samples offering a complementary technique to electron microscopy for histopathology assessment.

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references

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