High-resolution impedance mapping using electrically activated quantitative phase imaging

Cristina Polonschii; Mihaela Gheorghiu; Sorin David; Szilveszter Gáspár; Sorin Melinte; Hassaan Majeed; Mikhail E. Kandel; Gabriel Popescu; Eugen Gheorghiu

doi:10.1038/s41377-020-00461-x

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High-resolution impedance mapping using electrically activated quantitative phase imaging

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- High-resolution impedance mapping using electrically activated quantitative phase imaging
- High-resolution impedance mapping using electrically activated quantitative phase imaging
- LSA 2021年10卷第2期页码：186-196
- Affiliations：
  
  1.International Centre of Biodynamics, 060101 Bucharest, Romania
  2.Institute of Information and Communication Technologies, Electronics and Applied Mathematics, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium
  3.Quantitative Light Imaging Laboratory, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
- Author bio：
  
  Eugen Gheorghiu (gpopescu@illinois.edu)
  Gabriel Popescu (egheorghiu@biodyn.ro)
- Funds：
- DOI：10.1038/s41377-020-00461-x
  中图分类号：
- 纸质出版日期：2021，
  
  网络出版日期：2021-01-21，
  
  收稿日期：2020-07-14，
  
  修回日期：2020-12-16，
  
  录用日期：2020-12-29
- Accepted：
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High-resolution impedance mapping using electrically activated quantitative phase imaging[J]. LSA, 2021,10(2):186-196.

Polonschii, C. et al. High-resolution impedance mapping using electrically activated quantitative phase imaging. Light: Science & Applications, 10, 186-196 (2021).
High-resolution impedance mapping using electrically activated quantitative phase imaging[J]. LSA, 2021,10(2):186-196. DOI： 10.1038/s41377-020-00461-x.

Polonschii, C. et al. High-resolution impedance mapping using electrically activated quantitative phase imaging. Light: Science & Applications, 10, 186-196 (2021). DOI： 10.1038/s41377-020-00461-x.

摘要

Abstract

Retrieving electrical impedance maps at the nanoscale rapidly via nondestructive inspection with a high signal-to-noise ratio is an unmet need

likely to impact various applications from biomedicine to energy conversion. In this study

we develop a multimodal functional imaging instrument that is characterized by the dual capability of impedance mapping and phase quantitation

high spatial resolution

and low temporal noise. To achieve this

we advance a quantitative phase imaging system

referred to as epi-magnified image spatial spectrum microscopy combined with electrical actuation

to provide complementary maps of the optical path and electrical impedance. We demonstrate our system with high-resolution maps of optical path differences and electrical impedance variations that can distinguish nanosized

semi-transparent

structured coatings involving two materials with relatively similar electrical properties. We map heterogeneous interfaces corresponding to an indium tin oxide layer exposed by holes with diameters as small as ~550 nm in a titanium (dioxide) over-layer deposited on a glass support. We show that electrical modulation during the phase imaging of a macro-electrode is decisive for retrieving electrical impedance distributions with submicron spatial resolution and beyond the limitations of electrode-based technologies (surface or scanning technologies). The findings

which are substantiated by a theoretical model that fits the experimental data very well enable achieving electro-optical maps with high spatial and temporal resolutions. The virtues and limitations of the novel optoelectrochemical method that provides grounds for a wider range of electrically modulated optical methods for measuring the electric field locally are critically discussed.

关键词

Keywords

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