Bringing chiral functionality to in vivo applications of nanomaterials

Maria Mukhina

doi:10.1038/s41377-022-00841-5

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Bringing chiral functionality to in vivo applications of nanomaterials

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- Bringing chiral functionality to in vivo applications of nanomaterials
- Bringing chiral functionality to in vivo applications of nanomaterials
- LSA 2022年11卷第6期页码：1038-1039
- Affiliations：
  
  Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
- Author bio：
  
  Maria Mukhina (mmukhina@fas.harvard.edu)
- Funds：
- DOI：10.1038/s41377-022-00841-5
  中图分类号：
- 纸质出版日期：2022-06-30，
  
  网络出版日期：2022-05-27，
- Accepted：
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Bringing chiral functionality to in vivo applications of nanomaterials[J]. LSA, 2022,11(6):1038-1039.

Mukhina, M. Bringing chiral functionality to in vivo applications of nanomaterials. Light: Science & Applications, 11, 1038-1039 (2022).
Bringing chiral functionality to in vivo applications of nanomaterials[J]. LSA, 2022,11(6):1038-1039. DOI： 10.1038/s41377-022-00841-5.

Mukhina, M. Bringing chiral functionality to in vivo applications of nanomaterials. Light: Science & Applications, 11, 1038-1039 (2022). DOI： 10.1038/s41377-022-00841-5.

摘要

Abstract

Chirality is a universal property of an endless number of objects in the universe. Nanotechnology is rapidly expanding to find ways to introduce chirality to artificial nanostructures. In a recent publication in

Light: Science and Applications

Das et al. have successfully used capping with chiral ligand molecules to obtain chiral carbon dots. The authors provide a theoretical model to describe the origin of chirality in carbon dots as arising due to exciton coupling in a pair of chiral chromophores. Due to non-toxic chemical composition and sizes as small as 2–5 nm

the chiral carbon dots have the potential to outperform other chiral nanostructures in numerous biomedical applications. However

similarly to chiral drugs

their chiral toxicity must be well understood before the carbon dots are brought to living systems.

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references

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