Multifunctional transition and temperature-responsive contact lenses

Ahmed E. Salih; Haider Butt

doi:10.1038/s41377-023-01304-1

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Multifunctional transition and temperature-responsive contact lenses

Original Articles

- Multifunctional transition and temperature-responsive contact lenses
- Multifunctional transition and temperature-responsive contact lenses
- LSA 2023年12卷第12期页码：2624-2635
- Affiliations：
  
  Department of Mechanical Engineering, Khalifa University, Abu Dhabi, UAE
- Author bio：
  
  Ahmed E. Salih (aesalih95@gmail.com)
  Haider Butt (haider.butt@ku.ac.ae)
- Funds：
- DOI：10.1038/s41377-023-01304-1
  中图分类号：
- 纸质出版日期：2023-12-31，
  
  网络出版日期：2023-11-13，
  
  收稿日期：2023-05-02，
  
  修回日期：2023-09-22，
  
  录用日期：2023-10-10
- Accepted：
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Multifunctional transition and temperature-responsive contact lenses[J]. LSA, 2023,12(12):2624-2635.

Salih, A. E. & Butt, H. Multifunctional transition and temperature-responsive contact lenses. Light: Science & Applications, 12, 2624-2635 (2023).
Multifunctional transition and temperature-responsive contact lenses[J]. LSA, 2023,12(12):2624-2635. DOI： 10.1038/s41377-023-01304-1.

Salih, A. E. & Butt, H. Multifunctional transition and temperature-responsive contact lenses. Light: Science & Applications, 12, 2624-2635 (2023). DOI： 10.1038/s41377-023-01304-1.

摘要

Abstract

Smart contact lenses have recently gained traction due to their functionalization as noninvasive diagnostic and therapeutic wearables that can address several ocular diseases. Herein

multifunctional contact lenses exhibiting UV-transition and temperature-responsive capabilities were developed utilizing chromogenic materials that were integrated simultaneously into poly(2-hydroxyethyl methacrylate) (pHEMA) contact lenses. The functionalities of the contact lenses were optically evaluated in both their activated and non-activated states. Transition contact lenses offered excellent UV and blue light blocking capabilities (~45%) at their inactive states. When activated via UV exposure

the transparent lenses darkened instantaneously and absorbed portions of the visible light spectrum. The absorption intensity and transient discoloration of the transition lenses relied primarily on the utilized photochromic material. Likewise

the temperature-responsive contact lenses exhibited distinct colorimetric variations in response to temperature changes within the physiological range (33–38 ℃). The maximum sensitivity of the thermochromic lens was 8% transmitted light per Celsius degree shift. Physiochemical and morphological analysis indicated the adequacy of the contact lenses. Hence

the multifunctional contact lenses can be deployed as smart wearables to manage ophthalmic deficiencies that are deterred by UV radiations and variations in ocular surface temperature.

关键词

Keywords

references

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